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1. 发明公开

KR1020120108821A 발효 대두펩타이드와 풀빅산을 활성성분으로 포함한 산란율을 증가 및 저 콜레스테롤 계란 생산 효능을 가진 조성물 无效
标题翻译：用于改善含有作为活性成分的具有亲和性和作为活性成分的OY-BEAN发生肽的蛋白质比例和胆固醇含量的组合物
公开(公告)号：KR1020120108821A
公开(公告)日：2012-10-05
申请号：KR1020110027161
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수
IPC分类号： A23K1/18 , A23K1/16 , A23K1/14
CPC分类号： A23K10/30 , A23K10/16 , A23K50/75 , C12R1/125 , C12R1/46
摘要： PURPOSE: A composition having a low cholesterol egg production effect and an increasing effect on the oviposition rate is provided to use fermented soybean peptide and fulvic acid as active components. CONSTITUTION: A composition having a low cholesterol egg production effect and an increasing effect on the oviposition rate contains fermented soybean peptide and fulvic acid as active components. The fermented soybean peptide is obtained by fermenting soybean cake using Bacillus subtilis and Enterococcus faecium.
摘要翻译：目的：提供具有低胆固醇蛋产生效果和对产卵率的增加作用的组合物，以发酵大豆肽和富里酸为活性成分。构成：具有低胆固醇蛋产量效应和对产卵率的增加作用的组合物含有发酵大豆肽和富里酸作为活性成分。发酵大豆肽通过使用枯草芽孢杆菌和屎肠球菌发酵大豆饼获得。

2. 发明公开

KR1020120108814A 풀빅산의 탈취효과 无效
标题翻译：氟酸的去除效果
公开(公告)号：KR1020120108814A
公开(公告)日：2012-10-05
申请号：KR1020110027152
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： A61L9/01
CPC分类号： A61L9/01 , A61L2209/21
摘要： PURPOSE: A deodorization composition is provided to measure the concentration of ammonia, methylmercaptan, hydrogen sulfide, isovaleric acid, and propionic acid. CONSTITUTION: A deodorization composition includes fulvic acid as an active component. The fulvic acid removes 95% or more propionic acid, 87.5% or more methylmercaptan, 94% or more invalerate, 98% or more ammonia, and 50% or more hydrogen sulfoxide. The fulvic acid has improved profitability, availability, safety, and effectivity. [Reference numerals] (AA) Fermentation tank; (BB,CC,DD) Stirrer; (EE) Entrance
摘要翻译：目的：提供除臭组合物以测量氨，甲硫醇，硫化氢，异戊酸和丙酸的浓度。构成：除臭组合物包括作为活性组分的富里酸。该黄腐酸可除去95％以上的丙酸，87.5％以上的甲硫醇，94％以上的无水异氰酸酯，98％以上的氨，50％以上的氢亚砜。富里酸提高了利润率，可用性，安全性和有效性。（附图标记）（AA）发酵罐; （BB，CC，DD）搅拌器; （EE）入口

3. 发明公开

KR1020120108801A 활성성분으로 풀빅산을 포함하는 항알러지 조성물 无效
标题翻译：用于将包含作为活性组分的氟化物的过敏的组合物
公开(公告)号：KR1020120108801A
公开(公告)日：2012-10-05
申请号：KR1020110027131
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： A61K31/353 , A61K31/352 , A61P27/14
摘要： PURPOSE: An anti-allergic composition containing fulvic acid is provided to suppress the secretion of various allergic materials and to ensure excellent anti-allergic effect. CONSTITUTION: An anti-allergic composition contains fulvic acid as an active ingredient. Fulvic acid suppresses the secretion of allergic materials from mast cells causing allergy. The mast cells are RBL-2H3 cells. A method for preparing the mast cell RBL-2H3 comprises: a step of culturing mast cells in a medium containing glutamine, antibiotics, and 10% FBS; a step of collecting the mast cells by trypsin and culturing the mast cells with 200 ng/mL DNP-specific IgE; a step of washing the mast cells with PIPES buffer solution(25 mM PIPES, pH 7.2, 119 mM NaCl, 5 mM KCl, 0.4 mM MgCl_2, 1 mM CaCl_2, 5.6 mM glucose, and 0.1% BSA); a step of pre-culturing the mast cells for 30 minutes and adding 2ng/ml of antigen.
摘要翻译：目的：提供含有富酸的抗过敏组合物，以抑制各种过敏物质的分泌，并确保优异的抗过敏作用。构成：抗过敏组合物含有黄腐酸作为活性成分。富马酸抑制肥大细胞过敏物质的分泌，导致过敏。肥大细胞是RBL-2H3细胞。制备肥大细胞RBL-2H3的方法包括：在含有谷氨酰胺，抗生素和10％FBS的培养基中培养肥大细胞的步骤; 通过胰蛋白酶收集肥大细胞并用200ng / mL DNP特异性IgE培养肥大细胞的步骤; 用PIPES缓冲溶液（25mM PIPES，pH 7.2,119mM NaCl，5mM KCl，0.4mM MgCl 2，1mM CaCl 2，5.6mM葡萄糖和0.1％BSA）洗涤肥大细胞的步骤; 将肥大细胞预培养30分钟并加入2ng / ml抗原的步骤。

4. 发明公开

KR1020120108797A 활성물질로 풀빅산을 포함하는 간질환 치료용 조성물 无效
标题翻译：防止皮肤酸痛的抗生素毒性
公开(公告)号：KR1020120108797A
公开(公告)日：2012-10-05
申请号：KR1020110027119
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： A61K31/353 , A61K31/352 , A61P1/16 , A61P1/00
摘要： PURPOSE: A composition containing fulvic acid is provided to recover liver function for alcoholic fatty liver and to prevent and treat acute hepatotoxicity. CONSTITUTION: A composition for treating liver diseases contains fulvic acid as an active ingredient. The liver diseases are alcoholic fatty liver. Fulvic acid has high biological activity and easily binds with mineral and urine. The function of recovering liver function of fulvic acid in a mouse with alcoholic fatty liver is tested by biochemical analysis. [Reference numerals] (AA) Water; (BB) 20% ethanol; (CC) 0.0001% FA + 20% ethanol; (DD) 0.001% FA + 20% ethanol; (EE) 0.01% FA + 20% ethanol; (FF) 0.01% FA; (GG) 0.01% FA + 0.01% HA + 20% ethanol
摘要翻译：目的：提供含有富酸的组合物，以回收酒精性脂肪肝的肝功能，并预防和治疗急性肝毒性。构成：用于治疗肝脏疾病的组合物含有富里酸作为活性成分。肝脏疾病是酒精性脂肪肝。富酸具有很高的生物活性，易与矿物和尿液结合。通过生化分析检测酒精性脂肪肝小鼠肝脏功能恢复功能。（附图标记）（AA）水; （BB）20％乙醇; （CC）0.0001％FA + 20％乙醇; （DD）0.001％FA + 20％乙醇; （EE）0.01％FA + 20％乙醇; （FF）0.01％FA; （GG）0.01％FA + 0.01％HA + 20％乙醇

5. 发明授权

KR101294808B1 휴믹산을 활성성분으로 포함하는 증균용 조성물을 이용한 증균 방법 有权
标题翻译：细菌富集方法使用包含腐殖酸的细菌富集组合物
公开(公告)号：KR101294808B1
公开(公告)日：2013-08-08
申请号：KR1020110027117
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： C12N1/20 , C12N1/38
摘要： 본 발명은 천연 휴믹 물질(Natural Humic substances)에서 추출한 휴믹산의 증균 효과에 관한 것으로서, 보다 상세하게는 천연 휴믹 물질(Natural Humic substances)에 추출한 휴믹산을 활성 성분으로 포함하는 증균용 조성물을 이용한 증균방법에 관한 것이다. 본 발명은
Salmonella typhimurium,
Staphylococcus aureus ,
Enterococcus faecium 및
E. coli 로 이루어진 그룹에서 선택되는 어느 하나의 균을 ml당 10
5 cell로 희석한 균액과 휴믹산을 1%, 0.1% 및 0.01% 농도로 포함하는 증균용 조성물을 1:99의 비율로 혼합하여 10시간 동안 반응시킨 후, 배지에 상기 반응액을 도말하여 배양하는 것을 특징으로 하는 증균 방법을 제공한다.본 발명에 의하면 휴믹산이 증균 및 세포배양에 효과가 있는 것으로 확인되어 백신 개발 등에 도움을 줄 수 있는 증균용 조성물을 증균 방법을 제공할 수 있는 장점이 있다.

6. 发明公开

KR1020120108820A 풀빅산을 활성 성분으로 포함하는 항균 조성물 无效
标题翻译：包含油酸的细菌减少组合物
公开(公告)号：KR1020120108820A
公开(公告)日：2012-10-05
申请号：KR1020110027159
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： A61K31/353 , A61K31/352 , A61P31/04
摘要： PURPOSE: An antibacterial composition containing fulvic acid is provided to ensure antibacterial effect in antibiotic resistant strain and to suppress cell wall or membrane synthesis. CONSTITUTION: An antibacterial composition contains fulvic acid as an active ingredient. The fulvic acid is isolated from natural humic substances. The natural humic substance is formed of an erosion product of organic materials in soil and is detected in soil, water, deposit, charcoal, and peat. The natural humic substances are separated to fulvic acid and humic acid by solubility difference in acid. [Reference numerals] (AA) Immediately; (BB) 15 minutes later; (CC) 30 minutes later; (DD) One hour later
摘要翻译：目的：提供含有富里酸的抗菌组合物，以确保抗生素抗性菌株的抗菌作用，抑制细胞壁或膜合成。构成：抗菌组合物含有作为活性成分的富里酸。黄腐酸与天然腐殖质分离。天然腐殖质由土壤中有机物质的侵蚀产物形成，并在土壤，水，沉积物，木炭和泥炭中被检测出来。通过酸中的溶解度差异将天然腐殖质分离成富里酸和腐殖酸。（附图标记）（AA）立即; （BB）15分钟后（CC）30分钟后（DD）一小时后

7. 发明公开

KR1020120108809A 천연 응집 효과 및 악취 저감 효과를 가진 풀빅산을 활성성분으로 포함하는 수질 정화용 조성물 无效
标题翻译：用于水净化的组合物作为具有自然冷凝作用的活性组分和除去小麦粉的活性组分
公开(公告)号：KR1020120108809A
公开(公告)日：2012-10-05
申请号：KR1020110027143
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： C02F1/52
CPC分类号： C02F1/5263 , C02F2303/06 , C02F2303/22
摘要： PURPOSE: A water purifying composition containing fulvic acid with a natural coagulating function and a deodorizing function as an active component is provided to improve sludge decomposition effect by increasing dissolved oxygen. CONSTITUTION: A water purifying composition contains fulvic acid as an active component. The fulvic acid includes a natural coagulating function and a deodorizing function. The composition coagulates solid materials without an additional coagulant and removes bio films, which are formed on a cooling column, a draining pipe, and a water supplying line, when a liquid layer and a sludge layer are separated. [Reference numerals] (AA) Foreign specimen
摘要翻译：目的：提供含有具有天然凝结功能的富里酸和作为活性成分的除臭功能的净水组合物，以通过增加溶解氧来改善污泥分解效果。构成：水净化组合物含有作为活性组分的富里酸。富里酸包括天然凝结功能和除臭功能。当液体层和污泥层分离时，组合物凝固固体材料而没有附加的凝结剂，并且除去形成在冷却塔，排水管和供水管线上的生物膜。（附图标记）（AA）外国标本

8. 发明公开

KR1020120108808A 풀빅산을 활성성분으로 포함하는 항산화 조성물 无效
标题翻译：含有氟酸的抗氧化剂组合物
公开(公告)号：KR1020120108808A
公开(公告)日：2012-10-05
申请号：KR1020110027140
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： A61K31/353 , A61K31/352 , A61P39/06 , A61P39/00
摘要： PURPOSE: An antioxidation composition containing fulvic acid is provided to ensure excellent antioxidation effect and to suppress cytotoxicity. CONSTITUTION: An antioxidation composition contains fulvic acid as an active ingredient. The antioxidative effect of fulvic acid is measured using MTT assay in a dose-dependent manner. The antioxidative effect is also measured through DPPH assay. The antioxidation effect and cytotoxicity suppression of the fulvic acid are tested by LDH cytotoxicity assay.
摘要翻译：目的：提供含有富里酸的抗氧化组合物，以确保优异的抗氧化作用并抑制细胞毒性。构成：抗氧化组合物含有作为活性成分的富里酸。使用MTT法以剂量依赖的方式测定富里酸的抗氧化作用。还通过DPPH测定法测定抗氧化作用。通过LDH细胞毒性测定法测定黄腐酸的抗氧化作用和细胞毒性。

9. 发明公开

KR1020120108795A 휴믹산을 활성성분으로 포함하는 증균용 조성물을 이용한 증균 방법 有权
标题翻译：包含人体酸性的细菌增殖组合物
公开(公告)号：KR1020120108795A
公开(公告)日：2012-10-05
申请号：KR1020110027117
申请日：2011-03-25
申请人： 허교 , 손지영
发明人： 허교 , 손지영 , 장경수 , 나동희
IPC分类号： C12N1/20 , C12N1/38
摘要： PURPOSE: A bacterial enrichment composition containing humic acids isolated from natural humic substances is provided to develop vaccine. CONSTITUTION: A bacterial enrichment composition contains humic acids as an active ingredient. A method for isolating and purifying fulvic acid and humic acid from natural humic substances comprises: a step of treating the natural humic substance with strong base(NaOH, pH 10) and strong acid(HCl, pH 1); a step of precipitating humic acid to separate fulvic acid; and a step of purifying the fulvic acid by adsorption chromatography and cation exchange chromatography and dialysis.
摘要翻译：目的：提供一种含有从天然腐殖质分离的腐殖酸的细菌富集组合开发疫苗。构成：细菌富集组合物含有腐殖酸作为活性成分。从天然腐殖质分离和纯化富鲁酸和腐殖酸的方法包括：用强碱（NaOH，pH10）和强酸（HCl，pH 1）处理天然腐殖质的步骤; 沉淀腐殖酸分离黄腐酸的步骤; 以及通过吸附色谱法和阳离子交换色谱法和透析法纯化富里酸的步骤。

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