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1. 发明专利

JP2004265294A Web system for providing daily special menu, store information, and advertisement 审中-公开
公开(公告)号：JP2004265294A
公开(公告)日：2004-09-24
申请号：JP2003056875
申请日：2003-03-04
申请人： Takanori Kubo , 高憲久保
发明人： KUBO TAKANORI
IPC分类号： G06Q10/00 , G06Q30/02 , G06Q30/06 , G06Q50/00 , G06Q50/12 , G06F17/60
摘要： PROBLEM TO BE SOLVED: To provide a system that can communicate daily special menus of restaurants to many unspecified persons in remote locations, enable a search of daily special menus of a plurality of restaurants, and provide store information, advertisements and ordinary menu information as well as daily special menu information. SOLUTION: The system is so designed that daily special menu information on a plurality of stores is centrally stored in a server on the Internet, and with a Web function of a personal computer or cellular telephone, a CGI program on the server is executed through the Internet to process the centrally stored daily special menu information. For restaurants, a function capable of registering/editing daily special menus is provided, and for general persons, a search function is provided. The system can also centrally store store information, advertisements and ordinary menus as well as daily special menus and add respective store codes to handle the information on a store basis and provide it as well as daily special menu information. COPYRIGHT: (C)2004,JPO&NCIPI

2. 发明专利

JP2004185315A Daily merchandise information registration/retrieval system 审中-公开
公开(公告)号：JP2004185315A
公开(公告)日：2004-07-02
申请号：JP2002351477
申请日：2002-12-03
申请人： Takanori Kubo , 高憲久保
发明人： KUBO TAKANORI
IPC分类号： G06Q30/02 , G06Q30/06 , G06Q50/00 , G06F17/60
摘要： PROBLEM TO BE SOLVED: To provide a method for simply, quickly and inexpensively informing a consumer of merchandise information whose generation/erasure is repeated for a short period such as daily merchandise. SOLUTION: A table exclusive for daily merchandise information is prepared separately from normal information on the server of the Internet, and daily merchandise information existing across a plurality of stores/a plurality of classification items is stored in a batch, and a program and a user interface for registering/editing the information are prepared for a store, and a program and a user interface for retrieving the information are prepared for a consumer. COPYRIGHT: (C)2004,JPO&NCIPI

3. 发明专利

JP2004017261A Machining device, machining method, and machining system 审中-公开
公开(公告)号：JP2004017261A
公开(公告)日：2004-01-22
申请号：JP2002179739
申请日：2002-06-20
申请人： Takanori Kubo , Toshikatsu Nakajima , Naohiro Nishikawa , Shinya Tsukamoto , 中島利勝 , 久保孝典 , 塚本真也 , 西川尚宏
发明人： TSUKAMOTO SHINYA , NISHIKAWA NAOHIRO , KUBO TAKANORI , NAKAJIMA TOSHIKATSU
IPC分类号： B23P25/00
摘要： PROBLEM TO BE SOLVED: To provide a machining device, a machining method, and a machining system, wherein machining is performed without using processing liquid such as non-watersoluble working liquid and watersoluble working liquid.
SOLUTION: This machining device comprises: a tool such as a grind stone 8 for machining a conductive workpiece 9; a working liquid supplying nozzle 4 for supplying water 10 as working liquid to the workpiece 9 at the time of machining with a tool; and an anode part and a cathode part for flowing current to the workpiece 9. A processing liquid supplying nozzle 4 is used as the anode part, and a center 7 is used as the cathode part. The anode part and the cathode part are electrically connected with an anode and a cathode of a direct current power source supply/control device 1.
COPYRIGHT: (C)2004,JPO

4. 发明专利

JP2005117629A Exclusive compact information processor with electronic dictionary application and application for mobile telephone, and its connector cable 审中-公开
标题翻译：具有电子词典应用和移动电话应用的独特的紧凑信息处理器及其连接器电缆
公开(公告)号：JP2005117629A
公开(公告)日：2005-04-28
申请号：JP2004237312
申请日：2004-08-17
申请人： Takanori Kubo , 高憲久保
发明人： KUBO TAKANORI
IPC分类号： G06F17/30 , H04M1/00
摘要： PROBLEM TO BE SOLVED: To provide an exclusive compact information processor with an application for a mobile telephone and an electronic dictionary application which is light in weight, low in price and easy for a user to learn its operation. SOLUTION: The information processor 1 comprises a CPU 11, an input device 12, an output device 13, an storage device 14, and a communication device 15 to be connected to the mobile telephone. The storage device 14 stores the electronic dictionary application 141, the application for the mobile telephone 142, a communication processing program 143, and a means 144 for selecting/executing any one from the application for the mobile telephone and the electronic dictionary application. Components which are small in size, light in weight, low in price are selected for the devices, especially, the storage device 14 and the output device 13. Other components must have appropriate sizes, weight and prices, too. The information processor is further downsized by using the processor for a special purpose. COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：提供一种独特的紧凑型信息处理器，其具有重量轻，价格低廉并且易于用户学习其操作的移动电话和电子词典应用的应用。解决方案：信息处理器1包括要连接到移动电话的CPU 11，输入设备12，输出设备13，存储设备14和通信设备15。存储装置14存储电子词典应用141，移动电话142的应用，通信处理程序143和用于从移动电话和电子词典应用的应用中选择/执行任何一个的装置144。选择尺寸小，重量轻，价格低廉的部件，特别是存储装置14和输出装置13.其他部件也必须具有适当的尺寸，重量和价格。通过使用处理器进行特殊目的，信息处理器进一步小型化。版权所有（C）2005，JPO＆NCIPI

5. 发明授权

US10738304B2 Complex of polysaccharide and double-stranded RNA 有权
公开(公告)号：US10738304B2
公开(公告)日：2020-08-11
申请号：US12808504
申请日：2008-12-18
申请人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
发明人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
IPC分类号： C12N5/00 , C12N15/11 , C07H21/02
摘要： An object of the present invention is to provide novel double-stranded RNA having an RNA interference effect, in which the cellular uptake and the resistance to enzymatic degradation are improved, without reducing the RNA interference effect.The cellular uptake and the resistance to enzymatic degradation of a complex of a polysaccharide having a β-1,3-glucan skeleton and double-stranded RNA can be significantly improved while maintaining the RNA interference effect, by fulfilling the following conditions (i) to (iii): (i) the double-stranded RNA has a sense strand consisting of a base sequence complementary to a target sequence in a target gene and an antisense strand containing a base sequence complementary to the sense strand, and the double-stranded RNA can inhibit expression of the target gene; (ii) the double-stranded RNA has a single-stranded polydeoxyadenine bound directly or via a linker to the end of at least one of the sense strand and the antisense strand; and (iii) the polysaccharide and the single-stranded polydeoxyadenine form a complex.

6. 发明授权

US09040492B2 Double-stranded lipid-modified RNA having high RNA interference effect 有权
标题翻译：双链脂质修饰的RNA具有高RNA干扰作用
公开(公告)号：US09040492B2
公开(公告)日：2015-05-26
申请号：US12935546
申请日：2009-03-31
申请人： Takanori Kubo , Hideki Ohba , Hidekazu Toyobuku , Hirotake Hayashi
发明人： Takanori Kubo , Hideki Ohba , Hidekazu Toyobuku , Hirotake Hayashi
IPC分类号： A01N43/04 , C12N15/11
CPC分类号： C12N15/111 , C12N2310/3515 , C12N2320/32
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high resistance to nuclease and cellular uptake efficiency and that can produce an excellent RNA interference effect. The present invention provides a double-stranded lipid-modified RNA comprising an antisense strand having a nucleotide sequence complementary to a target sequence in a target gene, and a sense strand having a nucleotide sequence complementary to the antisense strand, the double-stranded RNA being capable of suppressing the expression of the target gene, and the sense strand having a double-stranded lipid bound directly or via a linker to at least one of the first to sixth nucleotides from the 5′ end.
摘要翻译：本发明的目的是提供对核酸酶和细胞摄取效率具有高抗性并且可以产生优异的RNA干扰效果的新型双链RNA。本发明提供了包含具有与靶基因中的靶序列互补的核苷酸序列的反义链和具有与反义链互补的核苷酸序列的有义链的双链脂质修饰的RNA，所述双链RNA为能够抑制靶基因的表达，并且将具有直链或经由连接基结合的双链脂质的有义链与5'末端的至少一个第一至第六个核苷酸结合。

7. 发明授权

US08981074B2 Lipid-modified double-stranded RNA having potent RNA interference effect 有权
标题翻译：脂质修饰的双链RNA具有强大的RNA干扰作用
公开(公告)号：US08981074B2
公开(公告)日：2015-03-17
申请号：US12738797
申请日：2008-10-24
申请人： Takanori Kubo , Hideki Ohba , Hidekazu Toyobuku , Hirotake Hayashi
发明人： Takanori Kubo , Hideki Ohba , Hidekazu Toyobuku , Hirotake Hayashi
IPC分类号： C07H21/04 , A61K47/48
CPC分类号： A61K47/48038 , A61K47/542 , A61K47/543
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high nuclease resistance and high cellular uptake efficiency, and that is capable of producing an excellent RNA interference effect. The present invention provides a lipid-modified double-stranded RNA comprising a sense strand having a nucleotide sequence complementary to a target sequence, and an antisense strand having a nucleotide sequence complementary to the sense strand, the double-stranded RNA being capable of inhibiting the expression of the target gene, the sense strand having a lipid linked to at least one of the first to sixth nucleotides from the 5′ end side directly or via a linker.
摘要翻译：本发明的目的是提供具有高核酸酶抗性和高细胞摄取效率的新型双链RNA，并能够产生优异的RNA干扰效果。本发明提供脂质修饰的双链RNA，其包含具有与靶序列互补的核苷酸序列的有义链和具有与有义链互补的核苷酸序列的反义链，所述双链RNA能够抑制靶基因的表达，有义链具有从5'末端侧的至少一个第一至第六个核苷酸直接或通过连接体连接的脂质。

8. 发明申请

US20110111501A1 COMPLEX OF POLYSACCHARIDE AND DOUBLE-STRANDED RNA 审中-公开
标题翻译：多糖和双链RNA的复合物
公开(公告)号：US20110111501A1
公开(公告)日：2011-05-12
申请号：US12808504
申请日：2008-12-18
申请人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
发明人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
IPC分类号： C12N5/00 , C07H21/02
CPC分类号： C12N15/111 , C12N2310/14 , C12N2310/3519 , C12N2320/32 , C12N2320/51
摘要： An object of the present invention is to provide novel double-stranded RNA having an RNA interference effect, in which the cellular uptake and the resistance to enzymatic degradation are improved, without reducing the RNA interference effect.The cellular uptake and the resistance to enzymatic degradation of a complex of a polysaccharide having a β-1,3-glucan skeleton and double-stranded RNA can be significantly improved while maintaining the RNA interference effect, by fulfilling the following conditions (i) to (iii): (i) the double-stranded RNA has a sense strand consisting of a base sequence complementary to a target sequence in a target gene and an antisense strand containing a base sequence complementary to the sense strand, and the double-stranded RNA can inhibit expression of the target gene; (ii) the double-stranded RNA has a single-stranded polydeoxyadenine bound directly or via a linker to the end of at least one of the sense strand and the antisense strand; and (iii) the polysaccharide and the single-stranded polydeoxyadenine form a complex.
摘要翻译：本发明的目的是提供具有RNA干扰效应的新颖的双链RNA，其中细胞摄取和对酶降解的抗性得到改善，而不降低RNA干扰效应。通过满足以下条件，可以显着改善具有β-葡聚糖骨架和双链RNA的多糖的复合物的细胞摄取和抗降解，同时保持RNA干扰效应（i）至（iii）：（i）双链RNA具有由与靶基因中的靶序列互补的碱基序列的有义链和含有与有义链互补的碱基序列的反义链，双链 RNA可抑制靶基因的表达; （ii）双链RNA具有单链多脱氧腺嘌呤，其直接或经由接头连接至至少一个有义链和反义链的末端; 和（iii）多糖和单链多脱氧腺嘌呤形成复合物。

9. 发明申请

US20100013577A1 BANDPASS FILTER, WIRELESS COMMUNICATION MODULE AND WIRELESS COMMUNICATION DEVICE 有权
标题翻译： BANDPASS滤波器，无线通信模块和无线通信设备
公开(公告)号：US20100013577A1
公开(公告)日：2010-01-21
申请号：US12567693
申请日：2009-09-25
申请人： Takanori KUBO , Hiromichi Yoshikawa
发明人： Takanori KUBO , Hiromichi Yoshikawa
IPC分类号： H01P3/08
CPC分类号： H01P1/20327 , H01P1/20354
摘要： A bandpass filter for a wide frequency band such as UWB is disclosed. The bandpass filter can receive a pair of signals, namely a balanced signal, and output a pair of signals. The bandpass filter comprises a plurality of ½ wavelength resonance electrodes, a plurality of ¼ wavelength resonance electrodes and a plurality of coupling electrodes. A transmission characteristic of the bandpass filter having flat and low loss over the entire region of the broad pass band can be achieved.
摘要翻译：公开了一种用于诸如UWB的宽频带的带通滤波器。带通滤波器可以接收一对信号，即平衡信号，并输出一对信号。带通滤波器包括多个1/2波长谐振电极，多个1/4波长谐振电极和多个耦合电极。可以实现在宽带的整个区域上具有平坦且低损耗的带通滤波器的传输特性。

10. 发明申请

US20100298411A1 LIPID-MODIFIED DOUBLE-STRANDED RNA HAVING POTENT RNA INTERFERENCE EFFECT 有权
标题翻译：脂质修饰双链RNA具有RNA干扰效应
公开(公告)号：US20100298411A1
公开(公告)日：2010-11-25
申请号：US12738797
申请日：2008-10-24
申请人： Takanori Kubo , Hideki Ohba , Hidekazu Toyobuku , Hirotake Hayashi
发明人： Takanori Kubo , Hideki Ohba , Hidekazu Toyobuku , Hirotake Hayashi
IPC分类号： A61K31/713 , C07H21/02 , C12N15/113 , A61P5/00
CPC分类号： A61K47/48038 , A61K47/542 , A61K47/543
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high nuclease resistance and high cellular uptake efficiency, and that is capable of producing an excellent RNA interference effect. The present invention provides a lipid-modified double-stranded RNA comprising a sense strand having a nucleotide sequence complementary to a target sequence, and an antisense strand having a nucleotide sequence complementary to the sense strand, the double-stranded RNA being capable of inhibiting the expression of the target gene, the sense strand having a lipid linked to at least one of the first to sixth nucleotides from the 5′ end side directly or via a linker.
摘要翻译：本发明的目的是提供具有高核酸酶抗性和高细胞摄取效率的新型双链RNA，并能够产生优异的RNA干扰效果。本发明提供脂质修饰的双链RNA，其包含具有与靶序列互补的核苷酸序列的有义链和具有与有义链互补的核苷酸序列的反义链，所述双链RNA能够抑制靶基因的表达，有义链具有从5'末端侧的至少一个第一至第六个核苷酸直接或通过连接体连接的脂质。

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