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1. 发明申请

WO2020251740A1 SYSTEM FOR DETECTING QRS COMPLEXES IN AN ELECTROCARDIOGRAPHY (ECG) SIGNAL 审中-公开
公开(公告)号：WO2020251740A1
公开(公告)日：2020-12-17
申请号：PCT/US2020/034173
申请日：2020-05-22
申请人： MURATA VIOS, INC. , RICCI, Carlos A. , KOVTUN, Vladimir V.
发明人： RICCI, Carlos A. , KOVTUN, Vladimir V.
IPC分类号： A61B5/04 , A61B5/00 , G06K9/00 , A61B5/0452
摘要： In one aspect, a computer-implemented method includes receiving a signal corresponding to electrical activity of a patient's heart; separating the signal into component signals; detecting fractional phase transitions for each of the component signals; generating, at each of the detected fractional phase transitions for each of the component signals, a data object containing a time value and an amplitude value; for a set of consecutive data objects associated with a first component signal of the component signals, detecting a peak amplitude; for a set of consecutive data objects associated with a second component signal of the component signals, detecting a peak amplitude; determining that the peak amplitudes satisfy a first time; calculating a consolidated peak amplitude and a consolidated peak time; and in response to determining that the consolidated peak amplitude satisfies both an amplitude criterion and a second time criterion, providing an indication of a detected heartbeat.

2. 发明申请

WO2007098228A2 SYSTEM AND METHOD OF MONITORING PHYSIOLOGICAL SIGNALS 审中-公开
标题翻译：监测生理信号的系统和方法
公开(公告)号：WO2007098228A2
公开(公告)日：2007-08-30
申请号：PCT/US2007/004556
申请日：2007-02-20
申请人： TRANSOMA MEDICAL, INC. , BROCKWAY, Brian, P. , KOVTUN, Vladimir , RICCI, Carlos , ARNOLD, John , JASPERSON, Keith , SHERWOOD, Kathy, L. , MAZAR, Scott, T.
发明人： BROCKWAY, Brian, P. , KOVTUN, Vladimir , RICCI, Carlos , ARNOLD, John , JASPERSON, Keith , SHERWOOD, Kathy, L. , MAZAR, Scott, T.
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/7275 , A61N1/3702 , G06F19/00
摘要： A physiological signal monitoring and analysis system including an implantable medical device and a signal processor. The implantable medical device is configured to monitor and record sample segments of at least one physiological signal of a patient at time separated recording intervals over a time period. The signal processor configured to measure values of at least one selected characteristic of the at least one physiological signal from the recorded sample segments, to determine trend information representing a trend in the at least one selected characteristic based on the measured values, and to assess a risk of a physiological event to the patient based on the trend information.
摘要翻译：一种生理信号监测和分析系统，包括可植入医疗装置和信号处理器。可植入医疗装置被配置为在一段时间内以分开的时间间隔监视和记录患者的至少一个生理信号的样本片段。所述信号处理器被配置为测量来自记录的采样段的至少一个生理信号的至少一个所选特征的值，以基于所述测量值确定表示所述至少一个所选特征中的趋势的趋势信息，并且评估根据趋势信息向患者发生生理事件的风险。

3. 发明申请

WO2005002669A2 TACHYARRHYTHMIA DETECTION AND DISCRIMINATION BASED ON CURVATURE PARAMETERS 审中-公开
标题翻译：基于曲率参数的快速心律失常检测与判别
公开(公告)号：WO2005002669A2
公开(公告)日：2005-01-13
申请号：PCT/US2004/020723
申请日：2004-06-28
申请人： CARDIAC PACEMAKERS, INC. , SWEENEY, Robert, J. , RICCI, Carlos
发明人： SWEENEY, Robert, J. , RICCI, Carlos
IPC分类号： A61N1/362
CPC分类号： G06K9/00523 , A61B5/0245 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61B5/7264 , A61N1/362 , A61N1/3962
摘要： Estimating a frequency of a sampled cardiac rhythm signal and classifying the rhythm. The received signal is sampled and transformed into a curvature series. A lobe in the curvature series corresponds to a characteristic point in the sampled series. Characteristic points are selected based on a time of a lobe in the curvature series and, in one embodiment, an amplitude of the signal at the time of the lobe. A frequency of the sampled series is estimated by autocorrelating a function of the series of the characteristic points. In one embodiment, the function is a time difference function. The rhythm is classified by plotting the timewise proximity of characteristic points derived from an atrial signal with characteristic points derived from a ventricular signal. Regions of the plot are associated with a particular rhythm and the grouping of the data corresponds to the classification.
摘要翻译：估计采样心律信号的频率并分类节奏。接收到的信号被采样并转换成曲率序列。曲率系列中的波瓣对应于采样序列中的特征点。基于曲率序列中的波瓣的时间来选择特征点，并且在一个实施例中，选择波瓣时的信号的幅度。通过对一系列特征点的函数进行自相关来估计采样序列的频率。在一个实施例中，该功能是时间差功能。通过绘制从心房信号导出的特征点与由心室信号导出的特征点的时间接近性来对节律进行分类。图的区域与特定的节奏相关联，并且数据的分组对应于分类。

4. 发明申请

WO2005018738A1 SYSTEM AND METHOD FOR NOISE MEASUREMENT IN AN IMPLANTABLE CARDIAC DEVICE 审中-公开
标题翻译：可移植心脏装置中噪声测量的系统和方法
公开(公告)号：WO2005018738A1
公开(公告)日：2005-03-03
申请号：PCT/US2004/026993
申请日：2004-08-19
申请人： CARDIAC PACEMAKERS, INC. , PALREDDY, Surekha , RICCI, Carlos , LIN, Yayun
发明人： PALREDDY, Surekha , RICCI, Carlos , LIN, Yayun
IPC分类号： A61N1/362
CPC分类号： A61B5/0452 , A61B5/046 , A61B5/7221 , A61N1/37 , A61N1/3704 , A61N1/3718 , Y10S128/901
摘要： An implantable cardiac rhythm management device is configured to estimating the noise level and noise floor in a sensing channel by measuring the magnitude of signal in the sensing channel when noise is determined to be present or absent, respectively. The presence or absence of noise may be determined by computing the density of local peaks or inflection points in an electrogram waveform. The computed local peak density is then used to set or clear a noise flag, which signifies whether noise is present or not. A noise statistic computed from samples of the electrogram signal obtained through a sensing channel may then be used to estimate a noise level or a noise floor.
摘要翻译：可植入心律管理装置被配置为通过分别在确定噪声存在或不存在时通过测量感测通道中的信号的幅度来估计感测通道中的噪声电平和噪声底限。噪声的存在或不存在可以通过计算电描记图波形中局部峰值或拐点的密度来确定。然后使用计算的局部峰值密度来设置或清除噪声标志，其表示是否存在噪声。然后可以使用从通过感测通道获得的电描记图信号的样本计算的噪声统计量来估计噪声水平或噪声底噪。

5. 发明申请

WO2006091636A2 SYSTEM AND METHOD FOR SIGNAL DECOMPOSITION, ANALYSIS AND RECONSTRUCTION 审中-公开
标题翻译：信号分解，分析与重构的系统与方法
公开(公告)号：WO2006091636A2
公开(公告)日：2006-08-31
申请号：PCT/US2006/006196
申请日：2006-02-23
申请人： DIGITAL INTELLIGENCE, L.L.C. , RICCI, Carlos, A. , KOVTUN, Vladimir, V.
发明人： RICCI, Carlos, A. , KOVTUN, Vladimir, V.
IPC分类号： A61B5/04
CPC分类号： H03H17/0201 , A61B5/0006 , A61B5/04014 , A61B5/0432 , A61B5/044 , G06K9/00523
摘要： The present invention provides a system and method for representing quasi-periodic ("qp") waveforms comprising, representing a plurality of limited decompositions of the qp waveform, wherein each decomposition includes a first and second amplitude value and at least one time value. In some embodiments, each of the decompositions is phase adjusted such that the arithmetic sum of the plurality of limited decompositions reconstructs the qp waveform. These decompositions are stored into a data structure having a plurality of attributes. Optionally, these attributes are used to reconstruct the qp waveform, or patterns or features of the qp wave can be determined by using various patterning techniques. Some embodiments provide a system that uses software, embedded hardware or firmware to carry out the above-described method. Some embodiments use a computer-readable medium to store the data structure and/or instructions to execute the method.
摘要翻译：本发明提供一种用于表示准周期（“qp”）波形的系统和方法，包括表示qp波形的多个有限分解，其中每个分解包括第一和第二振幅值和至少一个时间值。在一些实施例中，每个分解被相位调整，使得多个有限分解的算术和重建qp波形。这些分解被存储到具有多个属性的数据结构中。可选地，这些属性用于重建qp波形，或者可以通过使用各种图案化技术来确定qp波的图案或特征。一些实施例提供使用软件，嵌入式硬件或固件来执行上述方法的系统。一些实施例使用计算机可读介质来存储用于执行该方法的数据结构和/或指令。

6. 发明申请

WO2007098228A3 SYSTEM AND METHOD OF MONITORING PHYSIOLOGICAL SIGNALS 审中-公开
标题翻译：监测生理信号的系统和方法
公开(公告)号：WO2007098228A3
公开(公告)日：2008-03-27
申请号：PCT/US2007004556
申请日：2007-02-20
申请人： TRANSOMA MEDICAL INC , BROCKWAY BRIAN P , KOVTUN VLADIMIR , RICCI CARLOS , ARNOLD JOHN , JASPERSON KEITH , SHERWOOD KATHY L , MAZAR SCOTT T
发明人： BROCKWAY BRIAN P , KOVTUN VLADIMIR , RICCI CARLOS , ARNOLD JOHN , JASPERSON KEITH , SHERWOOD KATHY L , MAZAR SCOTT T
IPC分类号： A61B5/0464
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/7275 , A61N1/3702
摘要： A physiological signal monitoring and analysis system including an implantable medical device and a signal processor. The implantable medical device is configured to monitor and record sample segments of at least one physiological signal of a patient at time separated recording intervals over a time period. The signal processor configured to measure values of at least one selected characteristic of the at least one physiological signal from the recorded sample segments, to determine trend information representing a trend in the at least one selected characteristic based on the measured values, and to assess a risk of a physiological event to the patient based on the trend information.
摘要翻译：一种生理信号监测和分析系统，包括可植入医疗装置和信号处理器。可植入医疗装置被配置为在一段时间内以分开的时间间隔监视和记录患者的至少一个生理信号的样本片段。所述信号处理器被配置为测量来自记录的采样段的至少一个生理信号的至少一个所选特征的值，以基于所述测量值确定表示所述至少一个所选特征中的趋势的趋势信息，并且评估根据趋势信息向患者发生生理事件的风险。

7. 发明申请

WO2006091636A3 SIGNAL DECOMPOSITION AND RECONSTRUCTION 审中-公开
标题翻译：信号分解与重构
公开(公告)号：WO2006091636A3
公开(公告)日：2006-12-07
申请号：PCT/US2006006196
申请日：2006-02-23
申请人： DIGITAL INTELLIGENCE L L C , RICCI CARLOS A , KOVTUN VLADIMIR V
发明人： RICCI CARLOS A , KOVTUN VLADIMIR V
IPC分类号： A61B5/04
CPC分类号： H03H17/0201 , A61B5/0006 , A61B5/04014 , A61B5/0432 , A61B5/044 , G06K9/00523
摘要： The present invention provides a system and method for representing quasi-periodic ("qp") waveforms (1400) comprising, representin a plurality of limited decompositions of the qp waveform, wherein each decomposition includes a first and second amplitude value and at least one time value. In some embodiments, each of the decompositions is phase adjusted such that the arithmetic sum of the plurality of limited decompositions reconstructs the qp waveform. These decompositions are stored into a data structure having a plurality of attributes, Optionally, these attributes are used to reconstruct the qp waveform, or patterns or features of the qp wave can b determined by using various pattern-recognition techniques.
摘要翻译：本发明提供了一种用于表示准周期（“qp”）波形（1400）的系统和方法，包括：在多个限制性分解的qp波形中表示，其中每个分解包括第一和第二幅度值以及至少一次值。在一些实施例中，每个分解被相位调整，使得多个有限分解的算术和重建qp波形。这些分解被存储到具有多个属性的数据结构中。可选地，这些属性用于重建qp波形，或者通过使用各种模式识别技术确定的qp波的图案或特征。

8. 发明申请

WO2005002669A3 TACHYARRHYTHMIA DETECTION AND DISCRIMINATION BASED ON CURVATURE PARAMETERS 审中-公开
标题翻译：基于曲线参数的TACHYARRHYTHMIA检测和辨别
公开(公告)号：WO2005002669A3
公开(公告)日：2005-05-12
申请号：PCT/US2004020723
申请日：2004-06-28
申请人： CARDIAC PACEMAKERS INC , SWEENEY ROBERT J , RICCI CARLOS
发明人： SWEENEY ROBERT J , RICCI CARLOS
IPC分类号： A61B5/0245 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61N1/362 , A61N1/39 , G06K9/00 , G06F17/00
CPC分类号： G06K9/00523 , A61B5/0245 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/7239 , A61B5/7264 , A61N1/362 , A61N1/3962
摘要： Estimating a frequency of a sampled cardiac rhythm signal and classifying the rhythm. The received signal is sampled and transformed into a curvature series. A lobe in the curvature series corresponds to a characteristic point in the sampled series. Characteristic points are selected based on a time of a lobe in the curvature series and, in one embodiment, an amplitude of the signal at the time of the lobe. A frequency of the sampled series is estimated by autocorrelating a function of the series of the characteristic points. In one embodiment, the function is a time difference function. The rhythm is classified by plotting the timewise proximity of characteristic points derived from an atrial signal with characteristic points derived from a ventricular signal. Regions of the plot are associated with a particular rhythm and the grouping of the data corresponds to the classification.
摘要翻译：估计采样心律信号的频率并对节律进行分类。接收到的信号被采样并转换成曲率系列。曲率系列中的凸角对应于采样系列中的特征点。基于曲率序列中的波瓣的时间选择特征点，并且在一个实施例中，选择在波瓣时的信号的幅度。通过自相关一系列特征点的函数来估计采样序列的频率。在一个实施例中，该功能是时差功能。通过绘制从心房信号得到的特征点与从心室信号得到的特征点的时间接近，分类节律。地块的区域与特定节奏相关联，数据分组对应于分类。

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