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1. 发明公开

EP0833566A1 MODIFIED FAT BLENDS 失效
标题翻译： MODIFIZIERTE米施胖孩子
公开(公告)号：EP0833566A1
公开(公告)日：1998-04-08
申请号：EP96917203.0
申请日：1996-06-07
申请人： Perlman, Daniel , Hayes, Kenneth, C. , Massie, Cecil
发明人： Perlman, Daniel , Hayes, Kenneth, C. , Massie, Cecil
IPC分类号： A21D2 , A23D7 , A23D9
CPC分类号： A23D9/00 , A21D2/16 , A23D7/001
摘要： Blended cholesterol-reduced animal fat and vegetable oil which are combined in a proportion such that the weight ratio of linoleic acid (18:2) content divided by myristic acid (14:2) content is between 2 and 9 inclusive. In addition, cholesterol-reduced animal fat can be blended with cholesterol-reduced fish oil to stabilize the fish oil against air-oxidation at room temperature.

2. 发明公开

EP0833566A4 MODIFIED FAT BLENDS 失效
标题翻译： MODIFIZIERTE FETTMISCHUNGEN
公开(公告)号：EP0833566A4
公开(公告)日：2000-01-19
申请号：EP96917203
申请日：1996-06-07
申请人： PERLMAN DANIEL , HAYES KENNETH C , MASSIE CECIL
发明人： PERLMAN DANIEL , HAYES KENNETH C , MASSIE CECIL
IPC分类号： A21D2/16 , A23D7/00 , A23D9/00 , A23L5/20
CPC分类号： A23D9/00 , A21D2/16 , A23D7/001
摘要： Blended cholesterol-reduced animal fat and vegetable oil which are combined in a proportion such that the weight ratio of linoleic acid (18:2) content divided by myristic acid (14:2) content is between 2 and 9 inclusive. In addition, cholesterol-reduced animal fat can be blended with cholesterol-reduced fish oil to stabilize the fish oil against air-oxidation at room temperature.
摘要翻译：混合的胆固醇降低的动物脂肪和植物油以亚油酸（18：2）含量除以肉豆蔻酸（14：2）含量的重量比在2和9之间（包括2和9）的比例组合。此外，胆固醇降低的动物脂肪可以与胆固醇降低的鱼油混合，以稳定鱼油在室温下的空气氧化。

3. 发明申请

WO2012158018A3 COMPOSITIONS COMPRISING EXTRACTS OR MATERIALS DERIVED FROM PALM OIL VEGETATION LIGUOR FOR INHIBITION OF VISION LOSS DUE TO ANGIOGENESIS AND METHOD OF PREPARATION THEREOF 审中-公开
标题翻译：包含从棕榈油植物提取物提取的提取物或材料的组合物，用于抑制血液发生的视力损失及其制备方法
公开(公告)号：WO2012158018A3
公开(公告)日：2013-03-28
申请号：PCT/MY2012000102
申请日：2012-05-18
申请人： MALAYSIAN PALM OIL BOARD , MOGHADAM ALI HAFEZI , SAMBANTHAMURTHI RAVIGADEVI , TAN YEW AI , P MANICKAM KALYANA SUNDRAM , HAYES KENNETH C , SOUSKA ZANDI
发明人： MOGHADAM ALI HAFEZI , SAMBANTHAMURTHI RAVIGADEVI , TAN YEW AI , P MANICKAM KALYANA SUNDRAM , HAYES KENNETH C , SOUSKA ZANDI
IPC分类号： A61K36/889 , A61P3/00 , A61P3/10 , A61P17/00
CPC分类号： A61K36/889 , A23L33/105 , A61K31/05
摘要： The present invention relates generally to a composition comprising palm fruit juice for use in a method of preventing and inhibiting vision loss due to angiogenesis related diseases. The composition of the present invention aids to decrease in CNV size using confocal microscopy, in addition to reduction in macrophage infiltration using immune staining; decrease in VEGF- A-induced angiogenesis using established cornea pocket assay, inhibition of IKB-D phosphorylation in laser treated choroidal tissues and reduction in macrophage recruitment to CNV lesions.
摘要翻译：本发明一般涉及包含棕榈果汁的组合物，其用于预防和抑制由血管生成相关疾病引起的视力丧失的方法。本发明的组合物除了通过免疫染色减少巨噬细胞浸润外，还有助于使用共焦显微镜降低CNV大小; 使用已建立的角膜口袋测定法，激光治疗的脉络膜组织中IKB-D磷酸化的抑制以及巨噬细胞募集到CNV病变中的VEGF-A诱导的血管生成降低。

4. 发明申请

WO2009146102A1 METHODS FOR THE TREATMENT OR PREVENTION OF DIABETES MELLITUS AND OTHER METABOLIC IMBALANCES 审中-公开
标题翻译：治疗或预防糖尿病及其他代谢性不平衡的方法
公开(公告)号：WO2009146102A1
公开(公告)日：2009-12-03
申请号：PCT/US2009/039296
申请日：2009-04-02
申请人： BRANDEIS UNIVERSITY , MALAYSIAN PALM OIL BOARD , HAYES, Kenneth, C. , SUNDRAM, Kalyana , SAMBANTHAMURTHI, Ravigadevi , TAN, Yew, Ai
发明人： HAYES, Kenneth, C. , SUNDRAM, Kalyana , SAMBANTHAMURTHI, Ravigadevi , TAN, Yew, Ai
IPC分类号： A61K36/889 , A61P3/10 , A61K36/9068 , A61K31/216
CPC分类号： A61K31/192 , A61K2300/00
摘要： The invention relates to methods for treatment and prevention of a metabolic imbalance, including diabetes mellitus and other related diseases or disorders, using an extract from a fruit of genus Elaeis.
摘要翻译：本发明涉及使用来自水蛭属的果实的提取物治疗和预防代谢失调的方法，包括糖尿病和其它相关疾病或病症。

5. 发明申请

WO1996039857A1 MODIFIED FAT BLENDS 审中-公开
标题翻译：改性脂肪混合物
公开(公告)号：WO1996039857A1
公开(公告)日：1996-12-19
申请号：PCT/US1996008965
申请日：1996-06-07
申请人： PERLMAN, Daniel , HAYES, Kenneth, C. , MASSIE, Cecil
IPC分类号： A23D09/00
CPC分类号： A23D9/00 , A21D2/16 , A23D7/001
摘要： Blended cholesterol-reduced animal fat and vegetable oil which are combined in a proportion such that the weight ratio of linoleic acid (18:2) content divided by myristic acid (14:2) content is between 2 and 9 inclusive. In addition, cholesterol-reduced animal fat can be blended with cholesterol-reduced fish oil to stabilize the fish oil against air-oxidation at room temperature.
摘要翻译：将胆固醇降低的动物脂肪和植物油混合在一起，使得亚油酸（18:2）含量除以肉豆蔻酸（14：2）含量的重量比在2和9之间。此外，胆固醇降低的动物脂肪可以与胆固醇降低的鱼油混合，以稳定鱼油，防止室温下的空气氧化。

6. 发明申请

WO2010027433A2 SN-2 MYRISTATE-CONTAINING EDIBLE OIL 审中-公开
标题翻译： SN-2含糖食品
公开(公告)号：WO2010027433A2
公开(公告)日：2010-03-11
申请号：PCT/US2009/004860
申请日：2009-08-25
申请人： BRANDEIS UNIVERSITY , PERLMAN, Daniel , HAYES, Kenneth, C.
发明人： PERLMAN, Daniel , HAYES, Kenneth, C.
IPC分类号： A61K31/231
CPC分类号： C11C3/10 , A23D9/02 , A23L33/12
摘要： A nutritional fat or oil-based composition for increasing HDL cholesterol, decreasing LDL cholesterol and decreasing the LDL/HDL cholesterol ratio in human plasma is described. The composition can advantageously include at least 1 % by weight myristic acid esterified at the sn-2 position in triglyceride molecules, includes between 10% and 40% by weight linoleic acid, and further includes between 30% and 65% by weight oleic acid and between 15% and 40% by weight total saturated fatty acids. The ratio of sn-2 myristic acid to sn-2 palmitic acid is typically greater than 1 :1 and the sum of weight percentages for saturated, monounsaturated and polyunsaturated fatty acids equals 100%. In desirable cases, the composition is substantially cholesterol-free.
摘要翻译：描述了用于增加HDL胆固醇，降低LDL胆固醇和降低人血浆中LDL / HDL胆固醇比例的营养型油脂或组合物。该组合物可以有利地包括在甘油三酯分子中在sn-2位置酯化的至少1重量％的肉豆蔻酸，包括10重量％至40重量％的亚油酸，并且还包含30重量％至65重量％的油酸和 15％至40％（重量）的总饱和脂肪酸。 sn-2肉豆蔻酸与sn-2棕榈酸的比例通常大于1:1，饱和，单不饱和和多不饱和脂肪酸的重量百分比之和等于100％。在期望的情况下，组合物基本上不含胆固醇。

7. 发明申请

WO2012158018A2 COMPOSITIONS COMPRISING EXTRACTS OR MATERIALS DERIVED FROM PALM OIL VEGETATION LIGUOR FOR INHIBITION OF VISION LOSS DUE TO ANGIOGENESIS AND METHOD OF PREPARATION THEREOF 审中-公开
标题翻译：包含从棕榈油植物提取物提取的提取物或材料的组合物，用于抑制血液发生的视力损失及其制备方法
公开(公告)号：WO2012158018A2
公开(公告)日：2012-11-22
申请号：PCT/MY2012/000102
申请日：2012-05-18
申请人： MALAYSIAN PALM OIL BOARD , MOGHADAM, Ali Hafezi , SAMBANTHAMURTHI, Ravigadevi , TAN, Yew Ai , P MANICKAM, Kalyana Sundram , HAYES, Kenneth, C. , SOUSKA, Zandi
发明人： MOGHADAM, Ali Hafezi , SAMBANTHAMURTHI, Ravigadevi , TAN, Yew Ai , P MANICKAM, Kalyana Sundram , HAYES, Kenneth, C. , SOUSKA, Zandi
CPC分类号： A61K36/889 , A23L33/105 , A61K31/05
摘要： The present invention relates generally to a composition comprising palm fruit juice for use in a method of preventing and inhibiting vision loss due to angiogenesis related diseases. The composition of the present invention aids to decrease in CNV size using confocal microscopy, in addition to reduction in macrophage infiltration using immune staining; decrease in VEGF- A-induced angiogenesis using established cornea pocket assay, inhibition of IKB-D phosphorylation in laser treated choroidal tissues and reduction in macrophage recruitment to CNV lesions.
摘要翻译：本发明一般涉及包含棕榈果汁的组合物，其用于预防和抑制由血管生成相关疾病引起的视力丧失的方法。本发明的组合物除了通过免疫染色减少巨噬细胞浸润外，还有助于使用共焦显微镜降低CNV大小; 使用已建立的角膜口袋测定法，激光治疗的脉络膜组织中IKB-D磷酸化的抑制以及巨噬细胞募集到CNV病变中的VEGF-A诱导的血管生成降低。

8. 发明申请

WO2012151387A3 AMPHIPHILIC STEROL/FAT-BASED PARTICLES 审中-公开
公开(公告)号：WO2012151387A3
公开(公告)日：2012-11-08
申请号：PCT/US2012/036300
申请日：2012-05-03
申请人： BRANDEIS UNIVERSITY , PERLMAN, Daniel , HAYES, Kenneth, C. , PRONCZUK, Andrzej , CHAABO, Fadi
发明人： PERLMAN, Daniel , HAYES, Kenneth, C. , PRONCZUK, Andrzej , CHAABO, Fadi
IPC分类号： A23L1/035 , A23L2/52 , A23L1/30 , A23C9/152
摘要： The present invention relates to amphiphilic sterol- and fat-based particles, which can be dispersed in liquid foods and beverages such as milk. The compositions provided, when consumed, reduce low-density lipoprotein (LDL) and total plasma cholesterol (TC) levels.

9. 发明申请

WO0044237A2 HYPER-ABSORPTION OF VITAMIN E DISPERSED IN MILKS 审中-公开
标题翻译：维生素E在奶酪中的超吸收
公开(公告)号：WO0044237A2
公开(公告)日：2000-08-03
申请号：PCT/US0001597
申请日：2000-01-21
申请人： UNIV BRANDEIS , PERLMAN DANIEL , HAYES KENNETH C
发明人： PERLMAN DANIEL , HAYES KENNETH C
IPC分类号： A23C9/158 , A23C11/04 , A23C19/09 , A23L33/15 , A23C9/00
CPC分类号： A23C9/158 , A23C11/04 , A23C19/0921 , A23L33/15 , A23V2002/00 , A23V2250/5424 , A23V2250/712
摘要： A milk product including a level of at least 31IU vitamin E per serving of said product which can conveniently provide at least 100 IU of vitamin E per day to an individual ingesting the product. The vitamin E is uniformly microdispersed throughout the product, and ingestion of at least 100 IU of vitamin E per day in the product is sufficient to cause the fasting plasma vitamin E/cholesterol ratio in human subjects to be elevated at least 50 % above the basal fasting level of vitamin E measured in the same subjects consuming no vitamin E dietary supplements. A method for elevating the plasma vitamin E level at least 50 % in human subjects is also described. The method includes ingesting a milk product as described.
摘要翻译：一种含有至少31IU维生素E的奶制品，每份所述产品每天可以方便地提供至少100IU的维生素E至摄取产品的个体。维生素E在整个产品中均匀地微分散，并且每天在产品中摄入至少100IU的维生素E足以使人受试者的空腹血浆维生素E /胆固醇比例升高至基础以上至少50％维生素E的空腹水平在同一受试者中测量不消耗维生素E膳食补充剂。还描述了在人受试者中提高血浆维生素E水平至少50％的方法。该方法包括如上所述摄取牛奶制品。

10. 发明申请

WO2012151387A2 AMPHIPHILIC STEROL/FAT-BASED PARTICLES 审中-公开
标题翻译： AMPHIPHILIC STEROL / FAT-BASED PARTICLES
公开(公告)号：WO2012151387A2
公开(公告)日：2012-11-08
申请号：PCT/US2012036300
申请日：2012-05-03
申请人： UNIV BRANDEIS , PERLMAN DANIEL , HAYES KENNETH C , PRONCZUK ANDRZEJ , CHAABO FADI
发明人： PERLMAN DANIEL , HAYES KENNETH C , PRONCZUK ANDRZEJ , CHAABO FADI
IPC分类号： A23L1/035 , A23C9/152 , A23L1/30 , A23L2/52
CPC分类号： A23D9/013 , A23C9/152 , A23C11/103 , A23C2240/10 , A23D7/0053 , A23D7/011 , A23D9/007 , A23L23/00 , A23L27/60 , A23L29/10 , A23L33/11 , A23V2002/00 , A23V2200/222 , A23V2250/2136
摘要： The present invention relates to amphiphilic sterol- and fat-based particles, which can be dispersed in liquid foods and beverages such as milk. The compositions provided, when consumed, reduce low-density lipoprotein (LDL) and total plasma cholesterol (TC) levels.
摘要翻译：本发明涉及可分散在液体食品和饮料如牛奶中的两亲甾醇和脂肪基颗粒。当消耗时，提供的组合物降低低密度脂蛋白（LDL）和总血浆胆固醇（TC）水平。

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