发明申请
WO2022235966A1 UV A LIGHT EXPOSURE INCREASES MITOCHONDRIAL ANTI-VIRAL PROTEIN EXPRESSION IN TRACHEAL CELLS VIA CELL-TO-CELL COMMUNICATION AND USES THEREOF
审中-公开
基本信息:
- 专利标题： UV A LIGHT EXPOSURE INCREASES MITOCHONDRIAL ANTI-VIRAL PROTEIN EXPRESSION IN TRACHEAL CELLS VIA CELL-TO-CELL COMMUNICATION AND USES THEREOF
- 申请号：PCT/US2022/027915 申请日：2022-05-05
- 公开(公告)号：WO2022235966A1 公开(公告)日：2022-11-10
- 发明人： PIMENTEL, Mark , REZAIE, Ali , LEITE, Gabriela Guimaraes Sousa , MATHUR, Ruchi , MELMED, Gil Y.
- 申请人： CEDARS-SINAI MEDICAL CENTER
- 申请人地址： 8700 Beverly Boulevard
- 专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人： CEDARS-SINAI MEDICAL CENTER
- 当前专利权人地址： 8700 Beverly Boulevard
- 代理机构： ZHU, Suwei et al.
- 优先权： US63/184,749 2021-05-05
- 主分类号： A61B18/18
- IPC分类号： A61B18/18 ; B01J19/12
摘要：
Mitochondrial antiviral signaling (MAVS) protein mediates innate antiviral responses, and is an important component of the response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Herein methods are provided to increase expression of mitochondrial antiviral signaling (MAVS) protein in epithelial cells by use of a UVA therapy to expose the epithelial cells to the UVA therapy, or to contact a first set of epithelial cells with a second set of epithelial cells which have been exposed to the UVA therapy, or to contact a first set of epithelial cells with the cell lysates of the second set of epithelial cells that have been exposed to the UVA therapy.
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61B | 诊断；外科；鉴定 |
| ------A61B18/00 | 向人体或从人体传递非机械形式的能量的外科器械、装置或方法 |
| --------A61B18/18 | .通过实施电磁辐射，例如，微波 |