基本信息:
- 专利标题: STEVIOL GLYCOSYLTRANSFERASES AND GENES ENCODING THE SAME
- 申请号:PCT/US2021/034738 申请日:2021-05-28
- 公开(公告)号:WO2021243139A2 公开(公告)日:2021-12-02
- 发明人: LI, Xu , CHEN, Han-Yi , ANDERSON, Nickolas , WATERS, Amanda
- 申请人: QTG DEVELOPMENT, INC.
- 申请人地址: 555 West Monroe Street
- 专利权人: QTG DEVELOPMENT, INC.
- 当前专利权人: QTG DEVELOPMENT, INC.
- 当前专利权人地址: 555 West Monroe Street
- 代理机构: HASAN, Aisha R.
- 优先权: US16/887,435 2020-05-29
- 主分类号: C12N9/10
- IPC分类号: C12N9/10 ; C07K2319/21 ; C12N9/1048 ; C12N9/1051 ; C12P19/56 ; C12Y204/00 ; C12Y204/01
摘要:
Polynucleotides encoding corresponding polypeptides capable of glycosylating steviol at its C-19 position to produce a steviol glycoside, an expression vector including such a polynucleotide, a method for producing a steviol glycoside by culturing a recombinant host cell containing such an expression vector under conditions in which the cell expresses the UDP-glycosyltransferase from the polynucleotide, and a method for producing a steviol glycoside by contacting a composition including steviol with a recombinant UDP-glycosyltransferase. The steviol glycoside can be steviol-19-O-glycoside. The recombinant host cell containing such an expression vector can be a bacterial cell, a plant cell, or a fungal cell, an animal cell, or a multicellular organism such as a plant.