基本信息:
- 专利标题： MICROFLUIDIC DEVICE FOR CELL CULTURE IN GRADIENT OF BIOACTIVE SUBSTANCE
- 申请号：PCT/PL2017/000122 申请日：2017-12-08
- 公开(公告)号：WO2018106132A1 公开(公告)日：2018-06-14
- 发明人： SZAFRAN, Roman , GĄSIOROWSKI, Kazimierz , GĘBCZAK, Katarzyna , WIATRAK, Benita
- 申请人： POLITECHNIKA WROCŁAWSKA , UNIWERSYTET MEDYCZNY IM. PIASTÓW ŚLĄSKICH
- 申请人地址： Wybrzeże St. Wyspiańskiego 27 50-370 Wrocław PL
- 专利权人： POLITECHNIKA WROCŁAWSKA,UNIWERSYTET MEDYCZNY IM. PIASTÓW ŚLĄSKICH
- 当前专利权人： POLITECHNIKA WROCŁAWSKA,UNIWERSYTET MEDYCZNY IM. PIASTÓW ŚLĄSKICH
- 当前专利权人地址： Wybrzeże St. Wyspiańskiego 27 50-370 Wrocław PL
- 优先权： PLP.419754 20161209
- 主分类号： C12M3/00
- IPC分类号： C12M3/00 ; C12M1/00 ; B01L3/00 ; B81B7/00
摘要：
A multilayer microfluidic device for cell culture in the gradient of a bioactive substance characterised by three layers and two protective cups (3) of tanks, the top layer being a cover (6), which contains tanks of fluids feeding the culture chambers (1), reference points (4) and a millimetre graduation (5); in the middle functional layer (7), made of adhesive film, there is a set of channels serving as culture and indicator chambers (2) with semi-circular ends (8), at least one of which is intended for cell culture in concentration gradient of the active substance (culture chamber), one for cell culture without an active agent (blind test) and one to develop a concentration profile of the indicator substance (indicator chamber); and the bottom layer is the base (9).
IPC结构图谱:
| C | 化学；冶金 |
| --C12 | 生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程 |
| ----C12M | 酶学或微生物学装置 |
| ------C12M3/00 | 组织、人类、动物或植物细胞或病毒培养装置 |