发明申请
WO2014007759A1 METHODS RELATED TO REAL-TIME CANCER DIAGNOSTICS AT ENDOSCOPY UTILIZING FIBER-OPTIC RAMAN SPECTROSCOPY
审中-公开
基本信息:
- 专利标题： METHODS RELATED TO REAL-TIME CANCER DIAGNOSTICS AT ENDOSCOPY UTILIZING FIBER-OPTIC RAMAN SPECTROSCOPY
- 专利标题（中）：使用纤维光学拉曼光谱的内镜下实时癌症诊断相关的方法
- 申请号：PCT/SG2013/000273 申请日：2013-07-02
- 公开(公告)号：WO2014007759A1 公开(公告)日：2014-01-09
- 发明人： HUANG, Zhiwei , HO, Khek Yu , BERGHOLT, Mads Sylvest , ZHENG, Wei , YEOH, Khay Guan , DURAIPANDIAN, Shiyamala
- 申请人： NATIONAL UNIVERSITY OF SINGAPORE
- 申请人地址： 21 Lower Kent Ridge Road Singapore 119077 SG
- 专利权人： NATIONAL UNIVERSITY OF SINGAPORE
- 当前专利权人： NATIONAL UNIVERSITY OF SINGAPORE
- 当前专利权人地址： 21 Lower Kent Ridge Road Singapore 119077 SG
- 代理机构： AMICA LAW LLC
- 优先权： US61/667,384 20120702; GB1307338.2 20130423
- 主分类号： G01N21/65
- IPC分类号： G01N21/65 ; A61B5/00 ; G01J3/44 ; A61B6/00 ; G01N33/574
摘要：
A method of achieving instrument independent measurements for quantitative analysis of fiber-optic Raman spectroscope system, the system comprising a laser source, a spectroscope and a fiber optic probe to transmit light from the laser source to a target and return scattered light to the spectroscope, the method comprising transmitting light from the laser source to a standard target having a known spectrum, recording a calibration spectrum of the scattered light from the standard target, comparing the known spectrum and the calibration system and generating a probe and/or probe-system transfer function, and storing the transfer function. Further provided is a method of performing real-time diagnostic Raman spectroscopy optionally in combination with the other disclosed methods.
摘要（中）：
一种实现用于光纤拉曼光谱系统的定量分析的仪器独立测量的方法，该系统包括激光源，分光镜和光纤探针，以将来自激光源的光透射到目标物并将散射光返回到分光器， 所述方法包括将来自激光源的光传输到具有已知光谱的标准靶，记录来自标准靶的散射光的校准光谱，比较已知光谱和校准系统并产生探针和/或探针系统转移 功能，并存储传输功能。 进一步提供了可选地与其他公开的方法组合执行实时诊断拉曼光谱的方法。
IPC结构图谱:
| G | 物理 |
| --G01 | 测量；测试 |
| ----G01N | 借助于测定材料的化学或物理性质来测试或分析材料 |
| ------G01N21/00 | 利用光学手段，即利用红外光、可见光或紫外光来测试或分析材料 |
| --------G01N21/01 | .便于进行光学测试的装置或仪器 |
| ----------G01N21/63 | ..光学激发的 |
| ------------G01N21/65 | ...喇曼散射 |