基本信息:
- 专利标题: ANALYSIS OF MEASUREMENTS OF A POLYMER
- 专利标题(中):聚合物测量分析
- 申请号:PCT/GB2013/050381 申请日:2013-02-18
- 公开(公告)号:WO2013121224A1 公开(公告)日:2013-08-22
- 发明人: REID, Stuart William , CLARKE, James Anthony , WHITE, James , HARPER, Gavin
- 申请人: OXFORD NANOPORE TECHNOLOGIES LIMITED
- 申请人地址: Oxford Nanopore Technologies Limited Edmund Cartwright House 4 Robert Robinson Avenue Oxford Science Park GB
- 专利权人: OXFORD NANOPORE TECHNOLOGIES LIMITED
- 当前专利权人: OXFORD NANOPORE TECHNOLOGIES LIMITED
- 当前专利权人地址: Oxford Nanopore Technologies Limited Edmund Cartwright House 4 Robert Robinson Avenue Oxford Science Park GB
- 代理机构: MERRYWEATHER, Colin Henry
- 优先权: US61/599,573 20120216
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; B82Y15/00 ; G01N33/487 ; G06F19/22
摘要:
A time-ordered series of measurements of a polymer made during translocation of the polymer through a nanopore are analysed. The measurements are dependent on the identity of k-mers in the nanopore, a k-mer being k polymer units of the polymer, where k is a positive integer. The method involves deriving, from the series of measurements, a feature vector of time-ordered features representing characteristics of the measurements; and determining similarity between the derived feature vector and at least one other feature vector.
摘要(中):
分析了在聚合物通过纳米孔的位移期间制备的聚合物的时间有序的一系列测量。 测量取决于纳米孔中的k-mers的同一性,k-mer是聚合物的聚合物单元,其中k是正整数。 该方法包括从一系列测量中导出表示测量特征的时间有序特征的特征向量; 以及确定所导出的特征向量与至少一个其他特征向量之间的相似度。