基本信息:
- 专利标题： GASTRO-RETENTIVE DIAGNOSTIC ASSEMBLIES
- 专利标题（中）：胃恢复诊断组件
- 申请号：PCT/IL2006/000017 申请日：2006-01-05
- 公开(公告)号：WO2006072948A2 公开(公告)日：2006-07-13
- 发明人： AFARGAN, Michel , KIRMAYER, David , LAPIDOT, Noa , FRIEDMAN, Michael , HOFFMAN, Amnon
- 申请人： INTEC PHARMA LTD. , YISSUM RESEARCH DEVELOPMENT COMPANY , AFARGAN, Michel , KIRMAYER, David , LAPIDOT, Noa , FRIEDMAN, Michael , HOFFMAN, Amnon
- 申请人地址： 10 Hartom Street, 91450 Jerusalem IL
- 专利权人： INTEC PHARMA LTD.,YISSUM RESEARCH DEVELOPMENT COMPANY,AFARGAN, Michel,KIRMAYER, David,LAPIDOT, Noa,FRIEDMAN, Michael,HOFFMAN, Amnon
- 当前专利权人： INTEC PHARMA LTD.,YISSUM RESEARCH DEVELOPMENT COMPANY,AFARGAN, Michel,KIRMAYER, David,LAPIDOT, Noa,FRIEDMAN, Michael,HOFFMAN, Amnon
- 当前专利权人地址： 10 Hartom Street, 91450 Jerusalem IL
- 代理机构： REINHOLD COHN AND PARTNERS
- 优先权： IL166183 20050106
- 主分类号： A61K9/48
- IPC分类号： A61K9/48 ; A61K51/12 ; A61K49/18
摘要：
The present invention provides a gastro-retentive diagnostic assembly (GRDA) for use in determining a condition of a subject's gastrointestinal tract (GI tract), comprising a folded single or multi-layered device comprising a diagnostic utility, such as a contrasting agent, the device prior to folding being essentially planar, and included in a delivery system for oral intake, the delivery system being adapted to release the device once in the stomach, whereupon release said device unfolds into an unfolded shape that results in the retention of the device in the stomach. Further provided are methods of determining a condition of a subject's GI tract by the use of the GRDA of the invention, as well as uses of a single or multi-layered device comprising a diagnostic utility when in a folded or unfolded shape, and method of preparing the GRDA of the invention.
摘要（中）：
本发明提供用于确定受试者的胃肠道（胃肠道）状况的胃肠滞留性诊断组装体（GRDA），其包括折叠的单层或多层装置，所述装置包括诊断实用性 ，例如造影剂，折叠之前的装置基本上是平面的，并且包括在用于口服摄入的递送系统中，递送系统适于一旦在胃中释放装置，随后释放所述装置展开成展开形状， 导致装置在胃中的滞留。 进一步提供了通过使用本发明的GRDA确定受试者胃肠道状况的方法，以及当处于折叠或展开形状时包括诊断实用性的单层或多层装置的使用，以及 准备发明的GRDA。
IPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
| --------A61K9/48 | .胶囊制剂，例如用明胶、巧克力制造的 |