发明申请
WO2004009766A2 METHOD OF OBTAINING VIABLE HUMAN LIVER CELLS, INCLUDING HEPATIC STEM/PROGENITOR CELLS
审中-公开
基本信息:
- 专利标题： METHOD OF OBTAINING VIABLE HUMAN LIVER CELLS, INCLUDING HEPATIC STEM/PROGENITOR CELLS
- 专利标题（中）：获得可行的人肝细胞的方法，包括HEPATIC STEM / PROGENITOR CELLS
- 申请号：PCT/US0322220 申请日：2003-07-17
- 公开(公告)号：WO2004009766A2 公开(公告)日：2004-01-29
- 发明人： LUDLOW JOHN W , FURTH MARK E , BRUCE ANDREW T , REID LOLA M , SUSICK ROBERT L JR
- 申请人： INCARA CELL TECHNOLOGIES INC , LUDLOW JOHN W , FURTH MARK E , BRUCE ANDREW T , REID LOLA M , SUSICK ROBERT L JR
- 专利权人： INCARA CELL TECHNOLOGIES INC,LUDLOW JOHN W,FURTH MARK E,BRUCE ANDREW T,REID LOLA M,SUSICK ROBERT L JR
- 当前专利权人： INCARA CELL TECHNOLOGIES INC,LUDLOW JOHN W,FURTH MARK E,BRUCE ANDREW T,REID LOLA M,SUSICK ROBERT L JR
- 优先权： US39662902 2002-07-19
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; A61K35/407 ; A61K48/00 ; A61P1/16 ; C12N5/071 ; C12N5/0789 ; C12P21/02 ; G01N33/00 ; C12N
摘要：
The present invention is directed toward a method for obtaining from whole liver or a resection thereof a population of cells comprising viable, functional liver cells enriched in hepatocytes and hepatocyte stem/progenitor cells, compositions thereof, and uses therefore. Compositions include a composition of liver cells enriched in hepatocytes and hepatocyte stem/progenitor cells and a pharmaceutical composition thereof. Uses include treatment of liver diseases, regeneration of liver, toxicity testing and liver assist devices.
摘要（中）：
本发明涉及从整个肝脏或其切除方法获得包含富含肝细胞的活的功能性肝细胞和肝细胞干细胞/祖细胞的细胞群，以及其组合物及其用途。 组合物包括富含肝细胞的肝细胞和肝细胞干/祖细胞的组合物及其药物组合物。 用途包括肝脏疾病的治疗，肝脏再生，毒性试验和肝脏辅助装置。