发明申请
WO1988005781A1 NOVEL ANDROST-4-ENE-3,17-DIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
审中-公开
基本信息:
- 专利标题： NOVEL ANDROST-4-ENE-3,17-DIONE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
- 专利标题（中）：新型安慰剂4-ENE-3,17-Dione衍生物及其制备方法
- 申请号：PCT/JP1988000114 申请日：1988-02-05
- 公开(公告)号：WO1988005781A1 公开(公告)日：1988-08-11
- 发明人： SNOW BRAND MILK PRODUCTS CO., LTD.
- 申请人： SNOW BRAND MILK PRODUCTS CO., LTD. , YOSHIHAMA, Makoto , TAMURA, Koji , MIYATA, Nobuo , NAKAYAMA, Shoji , NAKAKOSHI, Masamichi
- 专利权人： SNOW BRAND MILK PRODUCTS CO., LTD.,YOSHIHAMA, Makoto,TAMURA, Koji,MIYATA, Nobuo,NAKAYAMA, Shoji,NAKAKOSHI, Masamichi
- 当前专利权人： SNOW BRAND MILK PRODUCTS CO., LTD.,YOSHIHAMA, Makoto,TAMURA, Koji,MIYATA, Nobuo,NAKAYAMA, Shoji,NAKAKOSHI, Masamichi
- 优先权： JP62/24594 19870206; JP62/24595 19870206; JP62/24598 19870206; JP62/24599 19870206
- 主分类号： C07J01/00
- IPC分类号： C07J01/00
摘要：
Compounds of formula (I), wherein X represents =O or H(alpha)OR(beta), Y represents H2 or OH(alpha)H(beta), Z represents H or OH(alpha), and R represents H, COCH3, COCH2CH3, COCH(CH3)2 or COC(CH3)3, which are prepared by bringing androst-4-ene-3,17-dione into contact with microorganisms belonging to the genus Acremonium. These compounds are effective in inhibiting estrogen synthetase of human placenta origin.