发明公开
US20230357781A1 LISTERIA-BASED COMPOSITIONS COMPRISING A PEPTIDE MINIGENE EXPRESSION SYSTEM AND METHODS OF USE THEREOF
审中-公开
基本信息:
- 专利标题： LISTERIA-BASED COMPOSITIONS COMPRISING A PEPTIDE MINIGENE EXPRESSION SYSTEM AND METHODS OF USE THEREOF
- 申请号：US18316539 申请日：2023-05-12
- 公开(公告)号：US20230357781A1 公开(公告)日：2023-11-09
- 发明人： Robert Petit , Michael F. Princiotta
- 申请人： Advaxis, Inc.
- 申请人地址： US NJ Princeton
- 专利权人： Advaxis, Inc.
- 当前专利权人： Advaxis, Inc.
- 当前专利权人地址： US NJ Princeton
- 主分类号： C12N15/74
- IPC分类号： C12N15/74 ; A61P35/00 ; A61K39/00 ; A61K35/74 ; C07K14/00 ; C12P21/02 ; C07K14/195 ; C07K14/82
摘要：
This disclosure provides compositions, including Listeria delivery vectors comprising minigene expression constructs, and methods of using the same for inducing an immune response against an antigen-expressing tumor and for treating the same, and vaccinating against the same in subjects bearing the tumors.