发明申请
US20210380941A1 Growth and Survival Compositions for Cells Capable of Producing Antibodies and Methods Related Thereto
有权
基本信息:
- 专利标题： Growth and Survival Compositions for Cells Capable of Producing Antibodies and Methods Related Thereto
- 申请号：US17406212 申请日：2021-08-19
- 公开(公告)号：US20210380941A1 公开(公告)日：2021-12-09
- 发明人： Frances Eun-Hyung Lee , Ignacio Sanz , Doan Nguyen
- 申请人： Emory University
- 申请人地址： US GA Atlanta
- 专利权人： Emory University
- 当前专利权人： Emory University
- 当前专利权人地址： US GA Atlanta
- 主分类号： C12N5/0781
- IPC分类号： C12N5/0781
摘要：
This disclosure relates to growth media and environments for in vitro culturing of cells that produce or are capable of producing antibodies. In certain embodiments, the media comprises IL-6, fibronectin, and typically a saccharide. In certain embodiments, the disclosure contemplates cell culture compositions comprising IL-6 and fibronectin that are derived from proteins secreted from mesenchymal stromal/stem cells (MSCs). In certain embodiments, the disclosure contemplates enclosures comprising culture compositions disclosed herein that are in ambient air or optionally in an environment wherein oxygen is absent or at a low concentration.