发明申请
US20200071301A1 Aryi, Heteroaryl, and Heterocyclic Pharmaceutical Compounds for Treatment of Medical Disorders
审中-公开
基本信息:
- 专利标题： Aryi, Heteroaryl, and Heterocyclic Pharmaceutical Compounds for Treatment of Medical Disorders
- 申请号：US16555914 申请日：2019-08-29
- 公开(公告)号：US20200071301A1 公开(公告)日：2020-03-05
- 发明人： Jason Allan Wiles , Avinash S. Phadke , Milind Deshpande , Atul Agarwal , Dawei Chen , Venkat Rao Gadhachanda , Akihiro Hashimoto , Godwin Pais , Qiuping Wang , Xiangzhu Wang , Joel Charles Barrish , William Greenlee , Kyle J. Eastman
- 申请人： Achillion Pharmaceuticals, Inc.
- 申请人地址： US CT New Haven
- 专利权人： Achillion Pharmaceuticals, Inc.
- 当前专利权人： Achillion Pharmaceuticals, Inc.
- 当前专利权人地址： US CT New Haven
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07F5/02 ; C07D471/08 ; C07D471/04 ; C07D403/14 ; C07D409/14 ; C07D491/107 ; C07D498/10
摘要：
Complement Factor D inhibitors, pharmaceutical compositions, and uses thereof, as well as processes for their manufacture are provided. The compounds provided include Formula I, Formula II, Formula III, Formula IV, and Formula V, or a pharmaceutically acceptable salt, prodrug, isotopic analog, N-oxide, or isolated isomer thereof, optionally in a pharmaceutically acceptable composition. The inhibitors described herein target Factor D and inhibit or regulate the complement cascade.
公开/授权文献:
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D401/00 | 杂环化合物，含有两个或更多个杂环，以氮原子作为仅有的杂环原子，至少有1个环是仅含有1个氮原子的六元环 |
| --------C07D401/14 | .含有3个或更多个杂环 |