基本信息:
- 专利标题： METHOD AND CATALYST FOR SYNTHESISING AZIRIDINE
- 申请号：US15675982 申请日：2017-08-14
- 公开(公告)号：US20170342030A1 公开(公告)日：2017-11-30
- 发明人： Sean Patrick Bew , Sean Michael Thurston , Paolo Pesce
- 申请人： University of East Anglia
- 优先权： GB1209840.6 20120601
- 主分类号： C07D203/02
- IPC分类号： C07D203/02 ; C07D413/06 ; C07D203/14 ; B01J31/02 ; C07D203/08 ; C07F9/24 ; C07D403/04
摘要：
The present invention relates to methods of synthesizing aziridines including isotopically labelled aziridines, said methods comprising contacting an imine or one or more precursors thereof with a diazo compound in the presence of a phosphoramide or a phosphoramide-derived catalyst. The present invention also relates to aziridines, modified aziridines and aziridine-derived compounds preparable by the aforementioned methods, and to phosphoramide or phosphoramide-derived catalysts suitable for use in such methods.
公开/授权文献:
- US10259784B2 Method and catalyst for synthesising aziridine 公开/授权日：2019-04-16
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D203/00 | 杂环化合物，含三元环、带1个氮原子作为惟一的杂环原子 |
| --------C07D203/02 | .通过闭环制备 |