
基本信息:
- 专利标题: Multilayer Hydrodynamic Sheath Flow Structure
- 专利标题(中):多层流体动力鞘流动结构
- 申请号:US13179084 申请日:2011-07-08
- 公开(公告)号:US20120009025A1 公开(公告)日:2012-01-12
- 发明人: John R. Gilbert , Manish Deshpande , Bernard Bunner
- 申请人: John R. Gilbert , Manish Deshpande , Bernard Bunner
- 申请人地址: US MA Boston
- 专利权人: CYTONOME/ST, LLC
- 当前专利权人: CYTONOME/ST, LLC
- 当前专利权人地址: US MA Boston
- 主分类号: B65G53/16
- IPC分类号: B65G53/16
摘要:
A microfabricated sheath flow structure for producing a sheath flow includes a primary sheath flow channel for conveying a sheath fluid, a sample inlet for injecting a sample into the sheath fluid in the primary sheath flow channel, a primary focusing region for focusing the sample within the sheath fluid and a secondary focusing region for providing additional focusing of the sample within the sheath fluid. The secondary focusing region may be formed by a flow channel intersecting the primary sheath flow channel to inject additional sheath fluid into the primary sheath flow channel from a selected direction. A sheath flow system may comprise a plurality of sheath flow structures operating in parallel on a microfluidic chip.
摘要(中):
用于产生鞘流的微细鞘层流动结构包括用于输送护套流体的初级鞘流动通道,用于将样品注入主鞘流道中的鞘液中的样品入口,用于将样品聚焦在 护套流体和辅助聚焦区域,用于提供样品在护套液体内的附加聚焦。 次要聚焦区域可以由与主鞘流道相交的流动通道形成,以从选定的方向将另外的鞘流体注入主鞘流动通道。 护套流动系统可以包括在微流体芯片上并行操作的多个护套流动结构。
公开/授权文献:
- US08529161B2 Multilayer hydrodynamic sheath flow structure 公开/授权日:2013-09-10