基本信息:
- 专利标题： CELL CULTURE SUPPORT AND ASSOCIATED METHOD FOR CELL GROWTH AND RELEASE
- 专利标题（中）：细胞培养支持和细胞生长和释放的相关方法
- 申请号：US12493331 申请日：2009-06-29
- 公开(公告)号：US20100330674A1 公开(公告)日：2010-12-30
- 发明人： Slawomir Rubinsztajn , Prameela Susarla , Anton Beletskii , Reginald Donovan Smith , Brian Polizzotti
- 申请人： Slawomir Rubinsztajn , Prameela Susarla , Anton Beletskii , Reginald Donovan Smith , Brian Polizzotti
- 申请人地址： US NY SCHENECTADY
- 专利权人： GENERAL ELECTRIC COMPANY
- 当前专利权人： GENERAL ELECTRIC COMPANY
- 当前专利权人地址： US NY SCHENECTADY
- 主分类号： C12N5/00
- IPC分类号： C12N5/00
摘要：
A cell culture support comprising a substrate, and a dual stimuli responsive block copolymer immobilized on the substrate, wherein the dual stimuli responsive block copolymer is both thermoresponsive and pH responsive. A method of culturing cells comprising the cell culture support having a dual stimuli responsive copolymer immobilized on a substrate, wherein the dual stimuli responsive copolymer is thermoresponsive and pH responsive; and growing the cells on the cell culture support. By lowering the temperature, cells are released from the cell culture support.
摘要（中）：
一种细胞培养支持物，其包含底物和固定在底物上的双重刺激响应性嵌段共聚物，其中所述双重刺激响应性嵌段共聚物是热反应性和pH响应性的。 一种培养细胞的方法，所述细胞包含具有固定在底物上的双重刺激响应共聚物的细胞培养支持物，其中所述双重刺激响应共聚物是热反应性和pH响应性的; 并在细胞培养支持下培养细胞。 通过降低温度，细胞从细胞培养支持物释放。