![Novel Immunomodulating Peptide](/abs-image/US/2007/12/06/US20070280954A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: Novel Immunomodulating Peptide
- 专利标题(中):新型免疫调节肽
- 申请号:US10556756 申请日:2004-05-14
- 公开(公告)号:US20070280954A1 公开(公告)日:2007-12-06
- 发明人: Lawrence Steinman , Hideki Garren , Paulo Fontoura
- 申请人: Lawrence Steinman , Hideki Garren , Paulo Fontoura
- 申请人地址: US CA Palo Alto 94306
- 专利权人: The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人: The Board of Trustees of the Leland Stanford Junior University
- 当前专利权人地址: US CA Palo Alto 94306
- 国际申请: PCT/US04/15387 WO 20040514
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; A61P37/02 ; G01N33/53
摘要:
Epitopic fragments of Nogo, including Nogo 45-66, elicit a specific and strong T cell response, and a B cell response. T cells reactive to Nogo antigens are capable of ameliorating ongoing disease, which may be induced with other antigens. The present invention provides compositions and methods for the identification and use of Nogo epitopic fragments in the treatment of immune related disease.
摘要(中):
Nogo的异位片段,包括Nogo 45-66,引发特异性和强T细胞应答和B细胞反应。 与Nogo抗原反应的T细胞能够改善正在进行的疾病,其可以用其他抗原诱导。 本发明提供用于鉴定和使用Nogo表位片段治疗免疫相关疾病的组合物和方法。
公开/授权文献:
- US07867976B2 Nogo epitopic fragments for modulating immune response 公开/授权日:2011-01-11
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K39/00 | 含有抗原或抗体的医药配制品 |