基本信息:
- 专利标题： Staphylococcus aureus genes & polypeptides
- 专利标题（中）：金黄色葡萄球菌基因和多肽
- 申请号：US10823785 申请日：2004-04-14
- 公开(公告)号：US20040265962A1 公开(公告)日：2004-12-30
- 发明人： Camella Bailey , Gil H. Choi
- 申请人： Human Genome Sciences, Inc.
- 申请人地址： US MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： US MD Rockville
- 主分类号： C07H021/04
- IPC分类号： C07H021/04 ; C12P021/04 ; C12N001/21 ; C07K014/315
摘要：
The present invention relates to novel genes from S. aureus and the polypeptides they encode. Also provided as are vectors, host cells, antibodies and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of S. aureus polypeptide activity. The invention additionally relates to diagnostic methods for detecting Staphylococcus nucleic acids, polypeptides and antibodies in a biological sample. The present invention further relates to novel vaccines for the prevention or attenuation of infection by Staphylococcus.
摘要（中）：
本发明涉及来自金黄色葡萄球菌的新基因及其编码的多肽。 还提供载体，宿主细胞，抗体以及用于制备它们的重组方法。 本发明还涉及用于鉴定金黄色葡萄球菌多肽活性的激动剂和拮抗剂的筛选方法。 本发明还涉及在生物样品中检测葡萄球菌核酸，多肽和抗体的诊断方法。 本发明还涉及用于预防或减轻葡萄球菌感染的新型疫苗。