![Method for immobilisation](/abs-image/US/2003/08/07/US20030148304A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: Method for immobilisation
- 专利标题(中):固定方法
- 申请号:US10165642 申请日:2002-06-07
- 公开(公告)号:US20030148304A1 公开(公告)日:2003-08-07
- 发明人: Zicai Liang , Anil Kumar
- 优先权: SE9904506-4 19991209
- 主分类号: C12Q001/68
- IPC分类号: C12Q001/68 ; B05D003/00 ; C07H021/02 ; C07H021/04 ; C12M001/34 ; C07K014/00
摘要:
A method for immobilisation of nucleic acids onto glass and silicon surfaces is described, wherein said nucleic acids are immobilised onto unmodified glass and other silicon surfaces. A new class of modified nucleic acids, namely silanised nucleic acids, and methods of preparing such modified nucleic acids, as well as a method for producing DNA chips of various density with only end-attachment of DNA applied, are also described.
摘要(中):
描述了将核酸固定在玻璃和硅表面上的方法,其中所述核酸固定在未改性的玻璃和其它硅表面上。 还描述了一类新的修饰的核酸,即硅烷化的核酸,以及制备这种修饰的核酸的方法,以及用于生产仅具有DNA末端附着的各种密度的DNA芯片的方法。