发明申请
US20030086944A1 Procedure for obtaining a titrated preparation from algae and the resultant titrated preparations
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基本信息:
- 专利标题： Procedure for obtaining a titrated preparation from algae and the resultant titrated preparations
- 专利标题（中）：从藻类和所得滴定制剂中获得滴定制剂的方法
- 申请号：US09947898 申请日：2001-09-06
- 公开(公告)号：US20030086944A1 公开(公告)日：2003-05-08
- 发明人： Gutierrez Gilles
- 优先权： FR01.09325 20010713
- 主分类号： A61K035/80
- IPC分类号： A61K035/80
摘要：
The present invention relates to the field of chemistry and more particularly to that of plant chemistry. Its specific aim is a process for obtaining powders or extracts from the alga Padina pavonica, titrated with active principles by means of a coefficient of equivalence with estradiol, which consists of dosing the extract or the powder of Padina pavonica using a method in which osteoblasts are cultivated in a medium rich in calcium ions, an analysis is made of the calcium fixed by the cells of the extracellular matrix in the presence or absence of agents antagonistic to the fixing of calcium, and the results are expressed either in arbitrary or international units in relation to a reference standard or by reference to the known activity of fixed doses of estradiol or of any other agent favouring the fixing of calcium.
摘要（中）：
本发明涉及化学领域，更具体地涉及植物化学领域。 其具体目标是从藻类Padina pavonica获得粉末或提取物的方法，用活性成分通过与雌二醇相当的系数滴定，该方法包括使用成骨细胞的方法给予提取物或粉末的Padina pavonica 在富含钙离子的培养基中培养，在存在或不存在拮抗钙固定的药剂存在下，分析由细胞外基质的细胞固定的钙，结果以任意或国际单位表示 与参考标准的关系，或通过参考固定剂量的雌二醇或有利于固定钙的任何其他药剂的已知活性。