发明申请
US20020155562A1 Glutathionylspermidine synthetase and processes for recovery and use thereof
审中-公开
![Glutathionylspermidine synthetase and processes for recovery and use thereof](/abs-image/US/2002/10/24/US20020155562A1/abs.jpg.150x150.jpg)
基本信息:
- 专利标题: Glutathionylspermidine synthetase and processes for recovery and use thereof
- 专利标题(中):谷胱甘肽合成酶及其回收利用方法
- 申请号:US09954433 申请日:2001-09-17
- 公开(公告)号:US20020155562A1 公开(公告)日:2002-10-24
- 发明人: Leopold Flohe , Kerstin Koenig , Ulrich Menge
- 申请人: Leopold Flohe
- 申请人地址: null
- 专利权人: Leopold Flohe
- 当前专利权人: Leopold Flohe
- 当前专利权人地址: null
- 优先权: EP96120014.4 19961212
- 主分类号: C07H021/04
- IPC分类号: C07H021/04 ; C12N009/00 ; C12N009/96 ; C12N001/00 ; C12N001/10 ; C07K002/00 ; C07K004/00 ; C07K005/00 ; C07K007/00 ; C07K014/00 ; C07K016/00 ; C07K017/00 ; A61K038/00 ; C07K001/00
摘要:
The present invention describes an enzyme showing glutathionylspermidine synthetase-activity and being distinct from known enzymes with similar activities in several physicochemical parameters, a novel process to isolate said enzyme from Crithidia fasciculata, tools for the production thereof in genetically transformed organisms, and its use as a molecular target for the discovery of trypanocidal drugs.
摘要(中):
本发明描述了一种酶,其显示出谷胱甘肽精氨酸合成酶活性,并且与几种物理化学参数中具有相似活性的已知酶不同,一种将所述酶与Crithidia fasciculata分离的新方法,用于在遗传转化的生物中生产的工具及其用途 发现杀真菌药物的分子靶点。