基本信息:
- 专利标题： 25-하이드록시비타민 D2 및 D3에 대한 항체 및 이들의 용도
- 专利标题（英）：ANTIBODIES TO 25-HYDROXYVITAMIN D2 AND D3 AND USES THEREOF
- 申请号：KR1020137033893 申请日：2012-05-18
- 公开(公告)号：KR102032531B1 公开(公告)日：2019-11-28
- 发明人： 캠벨,브루스,에이. , 린,스펜서,시앵-시 , 랴오,치뮤 , 사하키안,니버,파노시안 , 프리맨,제임스,빈센트 , 에반젤리스타,레이몬,에이.
- 申请人： 지멘스 헬쓰케어 다이아그노스틱스 인크.
- 申请人地址： *** Benedict Avenue, Tarrytown, NY *****, U.S.A.
- 专利权人： 지멘스 헬쓰케어 다이아그노스틱스 인크.
- 当前专利权人： 지멘스 헬쓰케어 다이아그노스틱스 인크.
- 当前专利权人地址： *** Benedict Avenue, Tarrytown, NY *****, U.S.A.
- 代理人： 특허법인 남앤남
- 优先权： US13/458,847 2012-04-27; US61/488,630 2011-05-20
- 国际申请： PCT/US2012/038637 2012-05-18
- 国际公布： WO2012162165 2012-11-29
- 主分类号： C07K16/26
- IPC分类号： C07K16/26 ; G01N33/53 ; G01N33/82
The antigenic molecule which can be used in order to generate the antibody combining with the vitamin d derivative, for example, 25- hydroxy calciferol and/or 25- hydroxy vitamin D3 or 25- hydroxy vitamin D analogue, for example, the vitamin D-C22 immunogenicity molecule or the compound is provided to the present application. The antibody generated using the antigenic molecule and related antigen compound is moreover written. Moreover, the method for detecting the vitamin D deficiency in the subject. The method for treating the subject which is regarded that it has the vitamin D deficiency, and the method for monitoring the progressing of the vitamin D deficiency in the subject and the method for monitoring the treatment of the vitamin D deficiency in the subject which need to monitor the treatment of the vitamin D deficiency are initiated in the present application. In the method and the biological sample for stabilizing the method for the detection of 25- hydroxy calciferol and D3 or the fixed quantity and reagent, and the vitamin D analogue, the method for separating 25- hydroxy calciferol and D3 from the Vitamin D binding protein is moreover provided.
公开/授权文献:
- KR1020140086925A 25-하이드록시비타민 D2 및 D3에 대한 항체 및 이들의 용도 公开/授权日：2014-07-08