基本信息:
- 专利标题： 조직 자가-회복 및 재생을 위한 치환된 방향족 화합물 및 약제학적 조성물
- 专利标题（英）：Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration
- 专利标题（中）：取代的芳香化合物和用于组织自体恢复和再生的药物组合物
- 申请号：KR1020177015741 申请日：2015-11-12
- 公开(公告)号：KR1020170072352A 公开(公告)日：2017-06-26
- 发明人： 객넌라인 , 라우린피에르
- 申请人： 프로메틱 파마 에스엠티 리미티드
- 申请人地址： Horizon Park, Barton Road, Comberton, Cambridge, United Kingdom CB** *AJ
- 专利权人： 프로메틱 파마 에스엠티 리미티드
- 当前专利权人： 프로메틱 파마 에스엠티 리미티드
- 当前专利权人地址： Horizon Park, Barton Road, Comberton, Cambridge, United Kingdom CB** *AJ
- 代理人： 제일특허법인
- 优先权： US62/078,704 2014-11-12
- 国际申请： PCT/CA2015/000572 2015-11-12
- 国际公布： WO2016074068 2016-05-19
- 主分类号： A61K31/192
- IPC分类号： A61K31/192 ; A61K8/36 ; A61K8/365 ; C07C57/30 ; C07C57/32 ; C07C57/58 ; C07C59/52 ; C07C59/84 ; A61Q19/08
Herein to include not only the compound or a pharmaceutically acceptable salt thereof, a medicament as possible, or a combination thereof of the formula I, their use has been described. These applications are self-organ tissue-recovery or organization to promote the regeneration, stimulates the production of tissue growth, tissue-regulation of the level of recovery marker (eg, increasing) the treatment, wound healing of organs within the physical damage to tissues or cells promoting not only include anti-aging purposes. The corresponding compositions, methods and uses are also described. Formula I:
Wherein, A is C
5 alkyl, C
6 alkyl, C
5 alkenyl, C
6 alkenyl, C (O) - (CH 2) n -CH 3 or
CH (OH) - (CH 2 ) n -CH 3 (where n is 3 or 4), and; R
1 is H, F or OH, and; R
2 is H, F, OH, C
5 alkyl, C
6 alkyl, C
5 alkenyl, C
6 alkenyl, C (0) - (CH 2) n -CH 3 or
CH (OH) - (CH 2 )
n -CH
3 (wherein n is 3 or 4), and; R
3 is H, F, OH, or CH
2 Ph, and; R
4 is H, F or OH; Q is
1) (CH 2) m C (0) OH ( wherein m is 1 or
2), 2) CH (CH 3 ) C (0) OH, 3) C (CH 3) 2 C (0) OH a, 4) CH (F) -C (0) OH, 5) CF 2 -C (0) OH , or 6) C (0) -C ( 0) OH.
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/045 | .羟基化合物，例如醇类；其盐类，例如醇化物 |
| ----------A61K31/19 | ..羧酸；例如丙戊酸 |
| ------------A61K31/192 | ...含芳族基团的，例如舒林酸、2芳基丙酸、依他尼酸 |