基本信息:
- 专利标题： 상처 치유를 촉진하기 위한 짧은 생체-활성 펩티드
- 专利标题（英）：Short bio-active peptides for promoting wound healing
- 专利标题（中）：短促生物活性肽促进创伤治疗
- 申请号：KR1020157024070 申请日：2014-01-21
- 公开(公告)号：KR1020150116883A 公开(公告)日：2015-10-16
- 发明人： 장리주안 , 카마이클로빈
- 申请人： 헬릭스 바이오메딕스, 인코포레이티드
- 申请人地址： *****-**th Ave SE #***, Bothell, WA *****, U.S.A.
- 专利权人： 헬릭스 바이오메딕스, 인코포레이티드
- 当前专利权人： 헬릭스 바이오메딕스, 인코포레이티드
- 当前专利权人地址： *****-**th Ave SE #***, Bothell, WA *****, U.S.A.
- 代理人： 송봉식; 정삼영
- 优先权： US61/764,913 2013-02-14
- 国际申请： PCT/US2014/012378 2014-01-21
- 国际公布： WO2014126681 2014-08-21
- 主分类号： C07K5/10
- IPC分类号： C07K5/10 ; C07K7/06 ; C07K14/435 ; A61K8/64 ; A61K38/16
The peptide having from 4 to 6 amino acid residues to retain the biological activity is disclosed. The peptide is composed of short peptide fragments of HB-107 (MPKEKVFLKIEKMGRNIRN), this is its own pin fragment of B antibacterial protein as Gocek shows a cell stimulation and migration properties. Peptide of the invention comprises a position 11, 16 and four to six contiguous amino acid residues located between the HB107 (MPKEKVFLKIEKMGRNIRN), i.e. EKMGRN. The disclosed peptide is, for skin damage, for example, a medicament useful in the veterinary treatment of diabetic ulcers. The peptide is also effective to prevent the surface of the skin damage resulting from a variety of environmental damage and reverse. Importantly, the therapeutic effect of the peptide appears at higher concentrations than the same or this peptide and HB-107, thus less expensive to develop effective treatments, further indicates that the flexible means. Production method and use of this peptide is also disclosed.
公开/授权文献:
- KR101894829B1 상처 치유를 촉진하기 위한 짧은 생체-활성 펩티드 公开/授权日：2018-09-05