基本信息:
- 专利标题: 증대된 환원활성을 나타내는 변이 메탄올 탈수소화 효소
- 专利标题(英):Mutated methanol dehydrogenase having improved reduction activity
- 专利标题(中):具有改进的还原活性的甲醇脱氢脱水
- 申请号:KR1020140023414 申请日:2014-02-27
- 公开(公告)号:KR1020150101752A 公开(公告)日:2015-09-04
- 发明人: 성봉현 , 이지연 , 손정훈 , 이승구
- 申请人: 한국생명공학연구원
- 申请人地址: ***, Gwahak-ro, Yuseong-gu, Daejeon, (***-***), Republic of Korea
- 专利权人: 한국생명공학연구원
- 当前专利权人: 한국생명공학연구원
- 当前专利权人地址: ***, Gwahak-ro, Yuseong-gu, Daejeon, (***-***), Republic of Korea
- 代理人: 손민
- 主分类号: C12N9/04
- IPC分类号: C12N9/04 ; C12P7/04 ; C12N15/70
The present invention is Bacillus meth fun is derived from Syracuse, reduction activity is increased mutated methanol dehydrogenation enzyme (MDH), expression vectors, transformation of the expression vector is introduced, including a polynucleotide, the polynucleotide encoding the enzyme body, will how to culture the transformant of the mutant produce a methanol dehydration digestive enzymes and by using the variation of methanol dehydrogenation enzyme relates to a method of producing methanol from formaldehyde. When variations of the present invention using the MDH, the reduction activity than the improved conventional MDH it possible to increase the production yield of the methanol will be widely utilized in the production of more efficient methanol.