基本信息:
- 专利标题： 소분자 화합물을 포함하는 만능성 줄기세포의 염색체 안정성 유지용 조성물
- 专利标题（英）：Composition for Maintaining Chromosome Stability of Pluripotent Stem Cells Comprising Small Molecules
- 专利标题（中）：维持包含小分子的多能干细胞染色体稳定性的组合物
- 申请号：KR1020140092074 申请日：2014-07-21
- 公开(公告)号：KR1020150013034A 公开(公告)日：2015-02-04
- 发明人： 홍성회 , 박항수 , 황인식 , 최경아 , 정혜선
- 申请人： 고려대학교 산학협력단
- 申请人地址： 서울특별시 성북구 안암로 ***, 고려대학교 (안암동*가)
- 专利权人： 고려대학교 산학협력단
- 当前专利权人： 고려대학교 산학협력단
- 当前专利权人地址： 서울특별시 성북구 안암로 ***, 고려대학교 (안암동*가)
- 代理人： 이처영; 장제환
- 优先权： KR1020130089205 2013-07-27
- 主分类号： C12N5/074
- IPC分类号： C12N5/074 ; C12N5/02
The present invention of relates to a composition for maintaining chromosome stability of the all-round sex stem cells, including small molecule compounds, while more particularly to de-differentiation stem cells (induced pluripotent stem cell) induction phase and derivation and subsequent cultivation of the chromosomal structure, ROCK inhibitors that may be numerically or inhibit mutant DNA damage, to a MEK inhibitor, ALK5 inhibitor or the composition for maintaining the stability of the all-round sex chromosome differentiation station stem cells containing the antioxidants. The composition for maintaining chromosome stability of the present invention station including a small molecule compound differentiation of the stem cells is to increase the speed and efficiency during cell de-differentiation stem production de-differentiation, a structural, soaking mutation inhibits or DNA damage inhibitory effect of the chromosome Great it is very useful for chromosome excellent stability de-differentiation stem cell therapy development.
公开/授权文献:
- KR101655383B1 소분자 화합물을 포함하는 만능성 줄기세포의 염색체 안정성 유지용 조성물 公开/授权日：2016-09-08