基本信息:
- 专利标题： 25-하이드록시비타민 D2 및 D3에 대한 항체 및 이들의 용도
- 专利标题（英）：Antibodies to 25-hydroxyvitamin d2 and d3 and uses thereof
- 专利标题（中）：25羟基维生素D2和D3的抗体及其用途
- 申请号：KR1020137033893 申请日：2012-05-18
- 公开(公告)号：KR1020140086925A 公开(公告)日：2014-07-08
- 发明人： 캠벨,브루스,에이. , 린,스펜서,시앵-시 , 랴오,치뮤 , 사하키안,니버,파노시안 , 프리맨,제임스,빈센트 , 에반젤리스타,레이몬,에이.
- 申请人： 지멘스 헬쓰케어 다이아그노스틱스 인크.
- 申请人地址： *** Benedict Avenue, Tarrytown, NY *****, U.S.A.
- 专利权人： 지멘스 헬쓰케어 다이아그노스틱스 인크.
- 当前专利权人： 지멘스 헬쓰케어 다이아그노스틱스 인크.
- 当前专利权人地址： *** Benedict Avenue, Tarrytown, NY *****, U.S.A.
- 代理人： 특허법인 남앤드남
- 优先权： US13/458,847 2012-04-27; US61/488,630 2011-05-20
- 国际申请： PCT/US2012/038637 2012-05-18
- 国际公布： WO2012162165 2012-11-29
- 主分类号： C07K16/26
- IPC分类号： C07K16/26 ; G01N33/53 ; G01N33/82
Vitamin D derivative, for example, 25-hydroxy vitamin D2 and / or 25-hydroxy-vitamin D3, or 25-hydroxy-vitamin D analogs, e.g., vitamin D-C22 can be coupled to an immunogenic molecule or compound the antigenic molecules are provided herein that can be used to generate antibodies. The antibodies generated using the antigen molecules, and related antigenic compounds are also described. In addition, a method for detecting a vitamin D deficiency in a subject. Method, a method for monitoring the progress of vitamin D deficiency in the subject, and the treatment of vitamin D deficiency in it is necessary to monitor the treatment of vitamin D deficiency subject to treat the subject is considered to have vitamin D deficiency the method for monitoring is disclosed herein. Method for 25-hydroxy vitamin D2 and to separate the method for the detection or quantification of the D3 and reagents, methods, and 25-hydroxy vitamin D2 and D3 from vitamin D binding protein in a biological sample for stabilizing the vitamin D analog of the also it is provided.
公开/授权文献:
- KR102032531B1 25-하이드록시비타민 D2 및 D3에 대한 항체 및 이들의 용도 公开/授权日：2019-11-28