基本信息:
- 专利标题： 고형 조직으로부터 세포를 접목시키는 방법
- 专利标题（英）：Method of engrafting cells from solid tissues
- 专利标题（中）：从固体组织中培养细胞的方法
- 申请号：KR1020127032025 申请日：2011-05-06
- 公开(公告)号：KR1020130108996A 公开(公告)日：2013-10-07
- 发明人： 터너,레이첼 , 거버,데이비드 , 로소야,오스왈도 , 레이드,롤라,엠.
- 申请人： 유니버시티 오브 노스캐롤라이나 앳 채플 힐
- 申请人地址： *** E. Cameron Avenue, *** Bynum Hall, CB #****, Chapel Hill, North Carolina *****-****, U.S.A.
- 专利权人： 유니버시티 오브 노스캐롤라이나 앳 채플 힐
- 当前专利权人： 유니버시티 오브 노스캐롤라이나 앳 채플 힐
- 当前专利权人地址： *** E. Cameron Avenue, *** Bynum Hall, CB #****, Chapel Hill, North Carolina *****-****, U.S.A.
- 代理人： 특허법인 무한
- 优先权： US61/332,441 2010-05-07
- 国际申请： PCT/US2011/035498 2011-05-06
- 国际公布： WO2011140428 2011-11-10
- 主分类号： C12N5/071
- IPC分类号： C12N5/071 ; A61K35/407 ; A61K35/42 ; A61K35/12
Long-term treatment of the disease which takes or dysfunction, or method is provided for establishing a model system of the diseased state. To treat long-term suffering from disease, the method comprising the extracellular matrix component, a signal molecule, a nutrient medium, the gel can be such that the speed for transplantation insoluble to form a graft-take the form biomaterials and mixed disease or function is related to a failure of the graft to the healthy tissue organs. In this method, the grafting is successful, and transplanted cells to integrate into and essentially microenvironment part or all of which was extended (expand) take the disease or dysfunction engine having at least one component to rebuild (rebuild) imitate the complexity of (the graft mimics the complexity of the native microenvironment with a minimum number of components that allow transplantation of cells to successfully engraft, expand and then rebuild part or the entirety of the diseased or dysfunctional organ). When using the grafting method for establishing a disease models, take the diseased cells may be implanted in the biomaterial and the experimental hosts.