基本信息:
- 专利标题: 이식가능한 약물전달 디바이스에 사용되기 위한 고체 약물 정제
- 专利标题(英):Solid drug tablets for implantable drug delivery devices
- 专利标题(中):用于可植入药物递送装置的固体药物片剂
- 申请号:KR1020127002112 申请日:2010-06-28
- 公开(公告)号:KR1020120090022A 公开(公告)日:2012-08-16
- 发明人: 이희진 , 라리비-엘킨스셰릴 , 다니엘카렌다니엘 , 헛친스3세벌리엠.
- 申请人: 타리스 바이오메디컬 엘엘씨
- 申请人地址: *** Hartwell Avenue, Lexington, Massachusetts *****, U.S.A.
- 专利权人: 타리스 바이오메디컬 엘엘씨
- 当前专利权人: 타리스 바이오메디컬 엘엘씨
- 当前专利权人地址: *** Hartwell Avenue, Lexington, Massachusetts *****, U.S.A.
- 代理人: 박장원
- 优先权: US61/220,865 2009-06-26; US61/241,382 2009-09-10
- 国际申请: PCT/US2010/040255 2010-06-28
- 国际公布: WO2010151896 2010-12-29
- 主分类号: A61M31/00
- IPC分类号: A61M31/00 ; A61K9/00 ; A61K9/20 ; A61K31/167
The drug dosage form of a solid tablet form containing at least 50% by weight of a local anesthetic is provided according to the present invention. Local anesthetics may be selected from amino amides, amino esters, and combinations thereof. Tablets containing the drug substance is less than 70% by weight and the other may be a vehicle in the form of mini-tablets. For example, the anesthetic may be in the lidocaine base or salt form, which is combined with excipients in a binder and a lubricant. Also it provides an implantable drug delivery device comprising the drug and, for example, the above-described drug tablet one or more may be contained within a biocompatible housing. Drug tablets may be in the fact that the flat end surface cylindrical shape, the device, there may be 10 to 100 drug tablets arranged in the housing in such a way that to the flat end surface of each of the drug adjacent to each other.
公开/授权文献:
- KR101710148B1 이식가능한 약물전달 디바이스에 사용되기 위한 고체 약물 정제 公开/授权日:2017-02-27