基本信息:
- 专利标题： 피리다지논, 그의 제조 방법 및 사용 방법
- 专利标题（英）：KR101864908B1 - Pyridazinones, method of making, and method of use thereof
- 申请号：KR20137008017 申请日：2011-08-31
- 公开(公告)号：KR101864908B1 公开(公告)日：2018-06-05
- 优先权： US37896410 2010-09-01
- 主分类号： C07D495/04
- IPC分类号： C07D495/04 ; A61K31/4985 ; A61P29/00 ; C07D487/04
摘要：
Btk 키나제를억제하기에그리고 Btk 키나제에의해매개된염증과같은면역장애를치료하기에유용한화학식 I의피리돈및 피라지논화합물(그의입체이성체, 호변이성체및 약제학적으로허용되는염을포함함). 포유류세포에서의그러한장애, 또는관련병리학적병태의시험관내(), 동일계내() 및생체내() 진단및 치료에있어서의화학식 I의화합물의사용방법이개시된다. [화학식 I]
摘要（英）：
To inhibit Btk kinase and useful pyridone and pyrazinone compounds of formula I in the treatment of immune disorders, such as the inflammation mediated by Btk kinase (including acceptable salts chemical their stereoisomers, tautomers and pharmaceutically) . Vitro of such disorders in mammalian cells, or associated pathological conditions
(in
vitro), in situ
(in
situ) and in vivo
(in
The
vivo) Usage of a compound of formula I in the diagnosis and treatment is started.
[Formula I]
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D495/00 | 杂环化合物，在稠环系中至少有1个杂环具有硫原子作为仅有的杂环原子 |
| --------C07D495/02 | .在稠环系中含有两个杂环 |
| ----------C07D495/04 | ..邻位稠合系 |