基本信息:
- 专利标题： 씨디22에 결합하는 인간 항체 및 이의 용도
- 专利标题（英）：Human antibodies and uses thereof that binds to CD 22
- 专利标题（中）：22个CD22的人体抗体及其用途
- 申请号：KR1020097013205 申请日：2007-11-30
- 公开(公告)号：KR101552735B1 公开(公告)日：2015-09-14
- 发明人： 킹,데이비드,죤 , 위트,앨리슨 , 레블랑크,헤이디,엔. , 쎄올리스,리챠드 , 마수드,아스나 , 야마나까,마크 , 젠스,키라,디. , 드위긴스,사라,아르. , 스프로울,팀 , 라오-나익,체타나 , 패스모어,데이비드 , 토이,크리스토퍼 , 타나마찌,돈엠.
- 申请人： 메다렉스, 엘.엘.시.
- 申请人地址： Route *** and Province Line Road, Princeton, New Jersey *****, USA
- 专利权人： 메다렉스, 엘.엘.시.
- 当前专利权人： 메다렉스, 엘.엘.시.
- 当前专利权人地址： Route *** and Province Line Road, Princeton, New Jersey *****, USA
- 代理人： 조용식
- 优先权： US60/868,231 2006-12-01
- 国际申请： PCT/US2007/086152 2007-11-30
- 国际公布： WO2008070569 2008-06-12
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; A61K39/395
The present invention provides monoclonal antibodies, particularly human monoclonal antibodies that specifically bind to the separated CD22 with high affinity. Also provided is a method for expressing the nucleic acid molecule encoding the antibody of the invention, expression vectors, host cells and antibodies of the present invention. In addition to the antibody it includes antibodies of the present invention provides a partner molecule conjugates, bispecific molecules and pharmaceutical compositions. In addition, the present invention relates to a method for detecting CD22, as well as by using an anti -CD22 antibody of the present invention provides a method for treating a variety of cancer and inflammatory and autoimmune disorders. Wherein -CD22 antibody, antibody-partner conjugates, tumor cell, cell toxins
公开/授权文献:
- KR1020090088920A 씨디22에 결합하는 인간 항체 및 이의 용도 公开/授权日：2009-08-20
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07K | 肽 |
| ------C07K16/00 | 免疫球蛋白，例如，单克隆或多克隆抗体 |
| --------C07K16/18 | .来自动物或人的抵抗物质 |
| ----------C07K16/28 | ..抗受体，细胞表面抗原或细胞表面决定因子 |