基本信息:
- 专利标题： Ｄｌｋ-1 유전자 발현억제용 조성물
- 专利标题（英）：Composition for inhibiting expression of Dlk-1 gene
- 专利标题（中）：用于抑制Dlk-1基因表达的组合物
- 申请号：KR1020110116215 申请日：2011-11-09
- 公开(公告)号：KR101414383B1 公开(公告)日：2014-07-10
- 发明人： 김상훈 , 김윤진 , 이학교 , 윤두학 , 서강석
- 申请人： 경희대학교 산학협력단
- 申请人地址： 경기도 용인시 기흥구 덕영대로 **** (서천동, 경희대학교 국제캠퍼스내)
- 专利权人： 경희대학교 산학협력단
- 当前专利权人： 경희대학교 산학협력단
- 当前专利权人地址： 경기도 용인시 기흥구 덕영대로 **** (서천동, 경희대학교 국제캠퍼스내)
- 代理人： 손민
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K31/7088 ; A61P35/00
The invention cancer for inhibiting the expression of Dlk-1 is overexpressed in cancer cells, including the miR-143 Dlk-1 composition for gene expression inhibition, comprising the expression micro-RNA of miR-143 to inhibit the Dlk-1 prevention or is overexpressed in the compositions and undifferentiated cells for the treatment relates to promoting differentiation for a micro RNA containing a miR-143, which inhibits the expression of Dlk-1 to inhibit the differentiation of undifferentiated cells composition. Composition comprising a miR-143 of the invention reduces the level of expression of Dlk-1 gene (pref-1), as well as to promote differentiation of all differentiated cells maintained by the expression of pref-1, pref-1 because the expression of tumor progression induced by the can be suppressed, will be widely used in the development of anticancer cell therapy or treatment using stem cells.
公开/授权文献:
- KR1020130051520A Ｄｌｋ-1 유전자 발현억제용 조성물 公开/授权日：2013-05-21
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K48/00 | 含有插入到活体细胞中的遗传物质以治疗遗传病的医药配制品；基因治疗 |