KR101391745B1 1,3-다이옥소인덴 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스용 약학적 조성물
有权
基本信息:
- 专利标题： 1,3-다이옥소인덴 유도체, 이의 약학적으로 허용되는 염 또는 이의 광학 이성질체, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스용 약학적 조성물
- 专利标题（英）：1,3-dioxane stamp den derivatives, pharmaceutically acceptable salts thereof or optical isomers thereof, production method thereof, and an antiviral pharmaceutical composition containing the same as an active ingredient
- 专利标题（中）：1,3-二氧代茚衍生物，其药学上可接受的盐，其制备方法和用于含有其作为活性成分的抗病毒药物组合物
- 申请号：KR1020120065023 申请日：2012-06-18
- 公开(公告)号：KR101391745B1 公开(公告)日：2014-05-07
- 发明人： 정영식 , 이종교 , 최일영 , 김해수 , 김필호 , 한수봉 , 렛츠요한 , 티바웃핸드릭
- 申请人： 한국화학연구원 , 카톨리에케 유니버시테이트 루벤
- 申请人地址： ***, Gajeong-ro, Yuseong-gu, Daejeon, *****, Republic of Korea
- 专利权人： 한국화학연구원,카톨리에케 유니버시테이트 루벤
- 当前专利权人： 한국화학연구원,카톨리에케 유니버시테이트 루벤
- 当前专利权人地址： ***, Gajeong-ro, Yuseong-gu, Daejeon, *****, Republic of Korea
- 代理人： 이원희
- 优先权： KR1020110058704 2011-06-16
- 主分类号： C07C49/665
- IPC分类号： C07C49/665 ; A61K31/47 ; A61K31/04 ; A61P31/12
The invention 1,3-dioxane derivative stamp Den, relates to a pharmaceutically acceptable salt thereof or an optical isomer thereof, methods for their preparation and pharmaceutical composition for the anti-virus containing the same as an active ingredient, the formula in accordance with the present invention; because of 1,3-dioxane derivatives Den stamp as well as low cytotoxicity, cocks ssaki virus, enterovirus types of the virus, echovirus, poliovirus, Rhino excellent antiviral activity against viruses in the blood or cor such as viruses, polio , paralysis, acute hemorrhagic conjunctivitis, viral meningitis, hand, foot and mouth disease, the number of artillery, A hepatitis, myositis, myocarditis, pancreatitis, diabetes, epidemic myalgia, encephalitis, flu, herpes guhyeop salts, foot-and-mouth disease, asthma, chronic obstructive pulmonary disease, It can be effectively used as a prophylactic or therapeutic pharmaceutical composition for viral diseases, such as pneumonia, sinusitis or otitis media.
公开/授权文献:
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07C | 无环或碳环化合物 |
| ------C07C49/00 | 酮；乙烯酮；二聚乙烯酮；酮的螯合物 |
| --------C07C49/04 | .有酮基连接在非环碳原子上的饱和化合物 |
| ----------C07C49/613 | ..多环的 |
| ------------C07C49/665 | ...酮基是稠环系的组成部分 |