基本信息:
- 专利标题: 앱타머 기반 표적지향 화학면역 요법
- 专利标题(英):Aptamer-based Targeted Chemoimmuno Therapy
- 专利标题(中):基于靶向的化学免疫治疗
- 申请号:KR1020100047567 申请日:2010-05-20
- 公开(公告)号:KR101229811B1 公开(公告)日:2013-02-05
- 发明人: 전상용 , 이인현
- 申请人: 광주과학기술원
- 申请人地址: 광주광역시 북구 첨단과기로 *** (오룡동)
- 专利权人: 광주과학기술원
- 当前专利权人: 광주과학기술원
- 当前专利权人地址: 광주광역시 북구 첨단과기로 *** (오룡동)
- 代理人: 양부현
- 主分类号: A61K9/32
- IPC分类号: A61K9/32 ; A61K47/30 ; A61P35/00 ; A61P37/00
The present invention relates to a material carrier (delivery system) comprising: (a) a biocompatible polymer carrier; (B) the first nucleic acid molecule covalently bonded to the biocompatible polymer; (C) nucleic acid molecule ligand having a targeting sequence that specifically bind to a complementary sequence and a target cell or tissue in the first nucleic acid molecule, the nucleic acid molecule ligand binds to the first nucleic acid molecule via the complementary sequences .; And (d) carrying the target (cargo) coupled to the nucleic acid molecule ligand. According to the present invention can provide an immune chemotherapeutics showing a simple, yet efficient the targeting. Immune chemotherapeutic agent of the invention is only transporting the drug to the target of interest and represents the effective therapeutic efficacy.
公开/授权文献:
- KR1020110127995A 앱타머 기반 표적지향 화학면역 요법 公开/授权日:2011-11-28
信息查询:
EspacenetIPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K9/00 | 以特殊物理形状为特征的医药配制品 |
--------A61K9/10 | .分散液;乳剂 |
----------A61K9/22 | ..持续释放或间断释放型 |
------------A61K9/30 | ...有机包衣层 |
--------------A61K9/32 | ....含固体合成聚合物的 |