基本信息:
- 专利标题： NOVEL PIPERIDINE DERIVATIVE AND PREPARATION THEREOF
- 申请号：JP348684 申请日：1984-01-13
- 公开(公告)号：JPS60149562A 公开(公告)日：1985-08-07
- 发明人： IRIKURA TSUTOMU , SHIBA TOSHIE , ABE YASUO , MATSUKUBO HIROSHI , SEKIGUCHI HARUO , TSURU KIYOSHI
- 申请人： KYORIN SEIYAKU KK
- 专利权人： KYORIN SEIYAKU KK
- 当前专利权人： KYORIN SEIYAKU KK
- 优先权： JP348684 1984-01-13
- 主分类号： C07D211/56
- IPC分类号： C07D211/56 ; A61K31/4427 ; A61K31/443 ; A61K31/445 ; A61P1/04 ; C07D211/00 ; C07D235/00 ; C07D317/00 ; C07D401/04 ; C07D401/06 ; C07D405/06
摘要：
NEW MATERIAL:A compound expressed by formula I [R is substituted benzoyl, substituted thiobenzoyl, (substituted) imidazolylmethyl, benzoylimidazole, N-methyl-N'-cyanoamidino or S-methyl-N-cyano-thiocarbamoyl; R -R are H, lower alkyl or lower alkoxyl; A is O or S] and a salt thereof. EXAMPLE:1-(3,40Methylenedioxythiobenzoyl)-3-(3,4,5-trimethoxybenzamido )piperidine. USE:An antiulcer agent capable of exhibiting effect on positive promotion of the repair of ulcerous tissues and prevention of the worsening by aggressive factors at the same time, and improvement in pain and other uncomfortable subjective symptoms. PREPARATION:A compound expressed by formula II is reacted with a compound expressed by formula III (X is halogen or methylmercapto) in an inert solvent at ordinary temperature - the boiling point of the solvent for several hours to afford the aimed compound expressed by formula I .
公开/授权文献:
- JPS60116854U 公开/授权日：1985-08-07
信息查询:
EspacenetIPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D211/00 | 杂环化合物，含氢化吡啶环，不与其他环稠合 |
| --------C07D211/04 | .只有氢或碳原子直接连在环氮原子上 |
| ----------C07D211/06 | ..环原子间或环原子与非环原子间无双键 |
| ------------C07D211/08 | ...有烃基或取代的烃基直接连在环碳原子上 |
| --------------C07D211/56 | ....氮原子 |