The present invention provides a compound or a pharmaceutically acceptable salt thereof of the formula (I) [wherein
[Formula 1]

^{Is, NR 10 -C (O) -NR} 9, S-C (O) -NR 9, NR 9 -C (O) -S, NR 9 -C (O) -O, CR 10 -C (O) ^{-NR 9, O-C (O} ) -NR 9, NR 10 -C (O) -CR 9, NR 10 -NR 9 -C (O), C (O) -NR 9 -NR 10, NR 10 - ^{N = CR 9, N = N} -CR 9, NR 10 -CR 9 = N, N = CR 9 -NR 10, NR 10 -N = N, N = N-NR 10, S-CR 9 = N or N = represents a ^{CR 9 -S, X 1} represents CR ¹ or N, respectively ^{X 2} and ^{X 3} independently represent ^{CR. 8} or ^{N, R 1, R 6,} R 8, R 9 and ^{R 10} each independently, hydrogen, halogen, _{hydroxy, (C 1 ~C 6) alkyl, (C 1 ~C 6)} alkoxy, hydroxy _{(C 1 ~C 6) alkoxy, (C 1 ~C 6)} alkoxy - (C _{1 ~C 6) alkyl, (C 1 ~C 6)} alkoxy _- (C 1 ~C 6) alkoxy, halo _{(C 1 ~C 6) alkyl, (C 1 ~C 6) alkylthio, (C 1 ~C 6} ) represents an alkylsulfinyl or _{(C 1 ~C 6)} ^{alkylsulfonyl, R 2, R 3, R} 4 and ^{R 5} are each independently, _{hydrogen, (C 1 ~C 6)} alkyl, halogen, halo _{(C 1 ~ C. 6)} alkyl or hydroxy _{(C 1 ~C 6)} alkyl, ^{R 7} is _{halogen, (C 1 ~C 6)} alkyl, halo _{(C 1 ~C 6) alkyl, (C 1 ~C 6)} alkoxy , hydroxy _{(C 1 ~C 6) alkoxy, (C 1 ~C 6)} alkoxy _- (C 1 ~C 6) _{alkyl, (C 1 ~C 6)} alkoxy _- (C 1 ~C 6) alkoxy, [(C _{1 ~C 6)} alkyl] NH- or _{[(C 1 ~C 6) alkyl} represents a 2 N-, provided that, (i)
## STR2 ##

If is representative of the ^{NR 10 -N = N} or ^{N = N-NR 10, R} 2 is _{(C 1 ~C 6)} alkyl, halogen, halo _{(C 1 ~C 6)} alkyl or hydroxy _{(C 1 ~C 6)} or represents an alkyl, or (ii)
## STR3 ##

There represents a ^{NR 10 -N = N} or ^N = N-NR 10, ^{when R 2} represents _{(C 1 ~C 6)} alkyl, ^{R 7} is _{halogen, (C 1 ~C 6)} alkyl, _{(C 1 -C. 6)} alkoxy, hydroxy _{(C 1 ~C 6) alkoxy, (C 1 ~C 6)} alkoxy _- (C 1 ~C 6) _{alkyl, (C 1 ~C 6)} alkoxy _{(C 1 ~C 6)} alkoxy _, [(C 1 ~C 6) alkyl] NH- or _{[(C 1 ~C 6) alkyl]} 2 N-represents a. These compounds are useful for treating a disease condition induced by excessive activity of VR1 receptors such as pain in a mammal. The invention further provides a pharmaceutical composition comprising said compound.
## STR00004 ##