
基本信息:
- 专利标题: VERFAHREN ZUR HERSTELLUNG VERZWEIGTER ALDEHYDE
- 专利标题(英):EP3380625A1 - Method for producing branched aldehydes
- 申请号:EP15808552.2 申请日:2015-11-28
- 公开(公告)号:EP3380625A1 公开(公告)日:2018-10-03
- 发明人: FRAATZ, Mario , ZORN, Holger , ROST, Johanna , GOLDMANN, Michael , GROSS, Egon , LEY, Jakob , GEISSLER, Katrin , GEISSLER, Torsten , BACKES, Michael , HENTSCHEL, Fabia , HILMER, Jens-Michael
- 申请人: Symrise AG
- 申请人地址: Mühlenfeldstrasse 1 37603 Holzminden DE
- 专利权人: Symrise AG
- 当前专利权人: Symrise AG
- 当前专利权人地址: Mühlenfeldstrasse 1 37603 Holzminden DE
- 代理机构: Eisenführ Speiser
- 国际公布: WO2017088937 20170601
- 主分类号: C12P7/24
- IPC分类号: C12P7/24 ; A23L2/56 ; C12P7/64
摘要:
The invention relates to a method for producing branched aldehydes, comprising the following steps: (a) providing a culture of one or more fungi of the genus
Conidiobolus and generating biomass containing branched carboxylic acids in a free and/or bonded form; (b) extracting the biomass from step (a) to generate a first intermediate product containing free and/or bonded carboxylic acids; (c) optionally chemically, enzymatically or microbially hydrolysing the bonded carboxylic acids from the first intermediate product; (d) treating the first intermediate product with a chemical-type reducing agent for transforming the free and/or bonded carboxylic acids into the corresponding alcohols, and optionally separating one or more alcohols from disruptive ancillary components and generating the chemically generated second intermediate product containing said alcohols as a mixture or in a concentrated form; (e) treating the first intermediate product with a biological-type reducing agent for transforming the free and/or bonded carboxylic acids into the corresponding aldehydes with the same number of carbon atoms compared to the free and/or bonded carboxylic acids, or into the corresponding aldehydes with a number of carbon atoms reduced by one compared to the free and/or bonded carboxylic acids, and generating the biologically generated second intermediate product containing said aldehydes; (f) treating the chemically generated second intermediate product with a chemical-type oxidising agent for transforming the free and/or bonded alcohols into the corresponding aldehydes; and optionally (g) removing disruptive ancillary components from the fractions obtained according to steps (d) and/or (e) and/or (f).
Conidiobolus and generating biomass containing branched carboxylic acids in a free and/or bonded form; (b) extracting the biomass from step (a) to generate a first intermediate product containing free and/or bonded carboxylic acids; (c) optionally chemically, enzymatically or microbially hydrolysing the bonded carboxylic acids from the first intermediate product; (d) treating the first intermediate product with a chemical-type reducing agent for transforming the free and/or bonded carboxylic acids into the corresponding alcohols, and optionally separating one or more alcohols from disruptive ancillary components and generating the chemically generated second intermediate product containing said alcohols as a mixture or in a concentrated form; (e) treating the first intermediate product with a biological-type reducing agent for transforming the free and/or bonded carboxylic acids into the corresponding aldehydes with the same number of carbon atoms compared to the free and/or bonded carboxylic acids, or into the corresponding aldehydes with a number of carbon atoms reduced by one compared to the free and/or bonded carboxylic acids, and generating the biologically generated second intermediate product containing said aldehydes; (f) treating the chemically generated second intermediate product with a chemical-type oxidising agent for transforming the free and/or bonded alcohols into the corresponding aldehydes; and optionally (g) removing disruptive ancillary components from the fractions obtained according to steps (d) and/or (e) and/or (f).
公开/授权文献:
- EP3380625B1 VERFAHREN ZUR HERSTELLUNG VERZWEIGTER ALDEHYDE 公开/授权日:2020-08-05
IPC结构图谱:
C | 化学;冶金 |
--C12 | 生物化学;啤酒;烈性酒;果汁酒;醋;微生物学;酶学;突变或遗传工程 |
----C12P | 发酵或使用酶的方法合成目标化合物或组合物或从外消旋混合物中分离旋光异构体 |
------C12P7/00 | 含氧有机化合物的制备 |
--------C12P7/24 | .含有羰基 |