基本信息:
- 专利标题： USE OF VITAMIN D RECEPTOR AGONISTS AND PRECURSORS TO TREAT FIBROSIS
- 申请号：EP08846682.6 申请日：2008-11-06
- 公开(公告)号：EP2209377B8 公开(公告)日：2018-09-05
- 发明人： EVANS, Ronald, M. , DOWNES, Michael , LIDDLE, Christopher
- 申请人： The Salk Institute For Biological Studies , University of Sydney
- 申请人地址： 10010 N. Torrey Pines Road La Jolla, CA 92037-1099 US
- 专利权人： The Salk Institute For Biological Studies,University of Sydney
- 当前专利权人： THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
- 当前专利权人地址： THE SALK INSTITUTE FOR BIOLOGICAL STUDIES
- 代理机构： Harrison IP Limited
- 优先权： US985972P 20071106
- 国际公布： WO2009061961 20090514
- 主分类号： A01N45/00
- IPC分类号： A01N45/00 ; A61K31/00 ; A61K31/592 ; A61K31/593 ; C12Q1/02 ; A61P1/16 ; A61P1/18 ; G01N33/82 ; G01N33/50
摘要：
This application relates to methods of treating, preventing, and ameliorating fibrosis, such as fibrosis of the liver, kidney, or pancreas. In particular, the application relates to methods of using a vitamin D receptor agonist (such as vitamin D, vitamin D analogs, vitamin D precursors, and vitamin D receptor agonists precursors) for the treatment of fibrosis. Also disclosed are methods for screening for agents that treat, prevent, and ameliorate fibrosis.