
基本信息:
- 专利标题: GENE EXPRESSED IN PROSTATE CANCER
- 专利标题(中):在前列腺癌基因表达
- 申请号:EP10000495.1 申请日:1999-09-30
- 公开(公告)号:EP2182064B1 公开(公告)日:2012-08-29
- 发明人: Afar, Daniel E. , Hubert, Rene S. , Mitchell, Stephen Chappell
- 申请人: Agensys, Inc.
- 申请人地址: 2225 Colorado Avenue Santa Monica, CA 90404 US
- 专利权人: Agensys, Inc.
- 当前专利权人: Agensys, Inc.
- 当前专利权人地址: 2225 Colorado Avenue Santa Monica, CA 90404 US
- 代理机构: Campbell, Patrick John Henry
- 优先权: US102572P 19980930; US146584P 19990728
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C07K14/47 ; C07K16/18 ; C12Q1/68 ; A01K67/027 ; A61K38/17 ; G01N33/53 ; G01N33/574
摘要:
A novel testis-specific gene expressed in human prostate cancer, designated 22P4F11, is described. Analysis of 22P4F11 mRNA expression in normal prostate, prostate tumor xenografts, and a variety of normal tissues indicates that the expression of this gene is testis specific in normal tissues. The 22P4F11 gene is also expressed in human prostate tumors, in some cases at high levels. A full length cDNA encoding 22P4F11 is provided. The 22P4F11 transcript and/or protein may represent a useful diagnostic marker and/or therapeutic target for prostate cancer.
公开/授权文献:
- EP2182064A1 GENE EXPRESSED IN PROSTATE CANCER 公开/授权日:2010-05-05