基本信息:
- 专利标题： DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS
- 专利标题（中）：双阳TRIARYLANALOGA为手段，以原生动物
- 申请号：EP04796320 申请日：2004-10-25
- 公开(公告)号：EP1682518A4 公开(公告)日：2007-08-01
- 发明人： BOYKIN DAVID W , TIDWELL RICHARD R , WILSON W DAVID , BRUN RETO , MOHAMED A ISMAIL
- 申请人： UNIV NORTH CAROLINA , UNIV GEORGIA STATE RES FOUND
- 专利权人： UNIV NORTH CAROLINA,UNIV GEORGIA STATE RES FOUND
- 当前专利权人： UNIV NORTH CAROLINA,UNIV GEORGIA STATE RES FOUND
- 优先权： US51416803 2003-10-24
- 主分类号： C07D235/18
- IPC分类号： C07D235/18 ; A61K31/4184 ; A61P31/00 ; C07D235/24 ; C07D307/71 ; C07D401/10 ; C07D405/10 ; C07D405/12 ; C07D405/14
摘要：
Novel dicationic, heterocyclic triaryl compounds are useful in the treatment of microbial infections, such as Trypanosoma brucei rhodesiense infection and Plasmodium falciparum infection. These compounds are accordingly useful in treating second-stage human African trypanosomiasis. Pharmaceutical formulations comprising these compounds can be used in methods of treating microbial infections.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D235/00 | 杂环化合物，含1,3-二唑或氢化1,3-二唑环、与其他环稠合 |
| --------C07D235/02 | .与碳环或碳环系稠合 |
| ----------C07D235/04 | ..苯并咪唑；氢化苯并咪唑 |
| ------------C07D235/18 | ...有芳基直接连在位置2 |