
基本信息:
- 专利标题: CONSENSUS/ANCESTRAL IMMUNOGENS
- 专利标题(中):一致/反应原免疫
- 申请号:EP04784298.4 申请日:2004-09-17
- 公开(公告)号:EP1667714A2 公开(公告)日:2006-06-14
- 发明人: HAYNES, Barton, F. , GAO, Feng , KORBER, Bette, T. , HAHN, Beatrice, H. , SHAW, George, M. , KOTHE, Denise , LI, Ying Ying , DECKER, Julie , LIAO, Hua-Xin
- 申请人: Duke University , The University of Alabama at Birmingham Research Foundation , The Regents of the University of California
- 申请人地址: P.O. Box 90083 Durham, NC 27708-0083 US
- 专利权人: Duke University,The University of Alabama at Birmingham Research Foundation,The Regents of the University of California
- 当前专利权人: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 当前专利权人地址: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- 代理机构: Atkinson, Peter Birch
- 优先权: US503460P 20030917; US604722P 20040827
- 国际公布: WO2005028625 20050331
- 主分类号: A61K39/21
- IPC分类号: A61K39/21 ; C07H21/04 ; C12N5/02 ; C12N15/74
摘要:
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.
摘要(中):
本发明一般涉及免疫原,特别涉及用于诱导中和广谱HIV原发分离株和/或诱导T细胞免疫应答的免疫原的抗体的免疫原。 本发明还涉及使用这种免疫原诱导抗HIV抗体的方法,和/或诱导T细胞免疫应答的方法。 本发明还涉及编码本发明免疫原的核酸序列。
公开/授权文献:
- EP1667714B1 CONSENSUS/ANCESTRAL IMMUNOGENS 公开/授权日:2018-01-03
IPC结构图谱:
A | 人类生活必需 |
--A61 | 医学或兽医学;卫生学 |
----A61K | 医用、牙科用或梳妆用的配制品 |
------A61K39/00 | 含有抗原或抗体的医药配制品 |
--------A61K39/12 | .病毒性抗原 |
----------A61K39/21 | ..反录病毒科,例如马染性贫血病毒 |