基本信息:
- 专利标题： MULTIVALENT SALTS OF PYRIDOSTIGMINE AND RELATED COMPOUNDS
- 专利标题（中）：吡啶斯的明和相关链接多价盐
- 申请号：EP97954835 申请日：1997-11-10
- 公开(公告)号：EP0941224A4 公开(公告)日：2000-01-12
- 发明人： GRANGER COLIN D , ORR ROBERT , RAMASAMY KANDASAMY
- 申请人： ICN PHARMACEUTICALS , GRANGER COLIN D , ORR ROBERT , RAMASAMY KANDASAMY
- 专利权人： ICN PHARMACEUTICALS,GRANGER COLIN D,ORR ROBERT,RAMASAMY KANDASAMY
- 当前专利权人： ICN PHARMACEUTICALS,GRANGER COLIN D,ORR ROBERT,RAMASAMY KANDASAMY
- 优先权： US3118696 1996-11-19
- 主分类号： C07D213/64
- IPC分类号： C07D213/64 ; C07D401/00 ; A61K31/27 ; A61K31/44 ; A61P21/04 ; A61P29/00 ; A61P43/00 ; C07C271/42 ; C07C271/52 ; C07D213/65 ; C07D239/34 ; C07D407/00 ; C07D401/06 ; C07C271/56 ; C07D401/08 ; C07D401/10 ; C07D401/12 ; C07D407/06 ; C07D407/08 ; C07D407/10 ; C07D407/12
摘要：
A quaternary ammonium cholinergic agent is complexed with a multivalent anion, or with multiple monovalent anions. The complex may be administered orally to a patient to treat pain, or for some other purpose. Numerous modifications are contemplated, including modifications to the ring structure of the compound, substitution and functionalization of the ring. Other contemplated modifications include the use of different anions, including various monovalent and polyvalent anions, and both organic and inorganic anions. The compounds have utility as cholinergic agents, and especially in the treatment of mysasthenia gravis, chest pain, and carpal tunnel syndrome.
IPC结构图谱:
| C | 化学；冶金 |
| --C07 | 有机化学 |
| ----C07D | 杂环化合物 |
| ------C07D213/00 | 杂环化合物，含六元环、不与其他环稠合、有1个氮原子作为仅有的杂环原子、环原子间或环原子与非环原子间有3个或更多个双键 |
| --------C07D213/02 | .环原子间或环原子与非环原子间有3个双键 |
| ----------C07D213/04 | ..在环氮原子与非环原子间没有键或只有氢或碳原子直接连在环氮原子上 |
| ------------C07D213/06 | ...除了环氮原子外，只含氢和碳原子 |
| --------------C07D213/62 | ....氧或硫原子 |
| ----------------C07D213/63 | .....1个氧原子 |
| ------------------C07D213/64 | ......连在位置2或6 |