基本信息:
- 专利标题：
- 申请号：DE60224052 申请日：2002-04-10
- 公开(公告)号：DE60224052D1 公开(公告)日：2008-01-24
- 发明人： HOLMES-FARLEY STEPHEN RANDALL , BURKE STEVEN K
- 申请人： GENZYME CORP
- 专利权人： GENZYME CORP
- 当前专利权人： GENZYME CORP
- 优先权： US28444501 2001-04-18; US30556701 2001-07-13
- 主分类号： A61K31/785
- IPC分类号： A61K31/785 ; A61K45/00 ; A61K31/519 ; A61K31/78 ; A61K31/787 ; A61K45/06 ; A61P3/00 ; A61P13/02 ; A61P13/12 ; A61P19/06
摘要：
A method for treating gout and/or reducing serum uric acid levels in a patient is disclosed that includes administering to the patient a therapeutically effective amount of an amine polymer, for example, an aliphatic amine polymer. In one embodiment, the polymer binds to uric acid or a precursor thereof. Examples of polymers useful in an embodiment of the invention include sevelamer hydrochloride and colesevelam. The invention includes the use of amine polymers such as a cross-linked polymer characterized by a repeat unit having the formula: and salts and copolymers thereof, where n is a positive integer and x is zero or an integer between 1 and about 4. Also described is a use, for the manufacture of a medicament, of a polymer that binds serum uric acid in a patient.
公开/授权文献:
- DE60224052T2 公开/授权日：2008-11-06
信息查询:
EspacenetIPC结构图谱:
| A | 人类生活必需 |
| --A61 | 医学或兽医学；卫生学 |
| ----A61K | 医用、牙科用或梳妆用的配制品 |
| ------A61K31/00 | 含有机有效成分的医药配制品 |
| --------A61K31/70 | .碳水化合物；糖；其衍生物 |
| ----------A61K31/785 | ..含有氮的聚合物 |