The invention relates to a high-temperature-resistant enameled wire prepared by 3D printing and a preparation method thereof, and belongs to the technical field of enamelled wires. The method is characterized in that conductive object powder is prepared into slurry or commercial conductive slurry is directly printed into a conductive inner core in a 3D printing mode, a high-temperature insulatingmaterial is prepared into thick slurry and then a high-temperature insulating material outer layer is obtained in the 3D printing mode; the conductive slurry or the powder is one or several kinds of graphene, graphite powder, carbon paste, conductive metal or modified ceramic; and the high-temperature-resistant insulating material is high-temperature-resistant insulating polyimide. The enameled wire prepared by the preparation method disclosed by the invention is excellent in mechanical property, chemical property, electrical property and thermal property; and the preparation method greatly simplifies the manufacturing process, the path can be designed, and the size can be customized, quick manufacturing is realized, and the method is particularly suitable for preparation of a small-diameter and micron-sized diameter enameled wire in batches, and provides a brand-new method for preparing the enameled wire.