The invention discloses a cleaning box for potato seed tubers. The cleaning box for the potato seed tubers comprises a box body, a water stop plate, a control rod, a drainage pipe, a seed tuber plate,springs, a bearing and a hand sliding door; the box body is a cube, the top and the internal are hollowed, a taking port is formed in the upper part of the front surface, and bearing holes are formedin the left and right sides; the water stop plate penetrates through the bearing, is fixedly mounted in the bearing holes of the box body, and is divided into upper and lower layers of drainage plates; the control rod is connected with each bearing end on the upper and lower layers of the drainage plates; the drainage pipe is mounted under the center of the box body; the springs are mounted underfour angles of the seed tuber plate; one sides of the springs are placed in the box body; and the hand sliding door is mounted in the taking port in the front surface of the box body. The cleaning box cannot damage the potato seed tubers when the potato seed tubers are conveniently cleaned, and is convenient to clean.