The invention provides an array substrate and a manufacturing method thereof, a display panel and a display module; the array substrate comprises data lines, grid lines and a bump unit, wherein the data lines and the grid lines are arranged in a display area, and the bump unit is arranged in a binding area; the bump unit comprises a plurality of grid line bump layers arranged on the same layer asthe grid lines, and data line bump layers arranged on the same layer as the data lines, wherein the grid line bump layers and the data lines are connected in a one-to-one correspondence mode; each grid line bump layer comprises a main body part and a plurality of hollow-out parts arranged in the main body part; the data line bump layers cover all the grid line bump layers; and the sum of the thickness of the data line bump layers and the thickness of each main body part is smaller than the thickness of the data line bump layer at each hollow-out part position. The array substrate provided by the invention has the same width as the single-layer area adopted in the prior art, the drawing force of the COF meets the requirements, so that the preparation of an ultra-narrow frame product can berealized.