The invention discloses a medical refuse incineration treatment device and relates to the technical field of medical treatment. The medical refuse incineration treatment device comprises a base. A first supporting frame is fixedly connected to the upper surface of the base. The bottom of the first supporting frame is fixedly connected with a connecting device. An incineration box is fixedly connected to the side, close to the center of the first supporting frame, of the connecting device. An air inlet device and a liquid spraying device are fixedly connected to the left and right sides of theupper surface of the incineration box correspondingly. According to the medical refuse incineration treatment device, a push frame is pushed through an eccentric disk to drive the incineration box toswing left and right, so that refuse in the incineration box is fully combined with oxygen in the air. The problems that the medical refuse is combusted insufficiently and the disposal efficiency of an existing medical refuse incineration treatment device is low due to the fact that the medical refuse incineration treatment device is poor in ventilation effect, and medical refuse cannot be fully combined with the oxygen in the air during combustion are solved effectively.