The invention discloses a full-automatic hydrofluoric acid production system, which is characterized by comprising a tank truck, a raw material storage tank, a rectification system, an intermediate tank circulation cooling and absorption system, a tail discharge system, a PLC control system and the like. The whole production process of hydrofluoric acid is controlled by the PLC control system, wherein the rectification system comprises a preheating tower, two filtering towers arranged in a two-stage parallel manner, reaction stills and a rectifying tower; and the intermediate tank circulation cooling and absorption system comprises intermediate tanks, two-stage cooling towers, second filtering towers and a center control detection system. The full-automatic hydrofluoric acid production system adopts liquid anhydrous hydrogen fluoride for preparing hydrofluoric acid, the design is novel and reasonable, the production process is controlled by the PLC control system, the safety is high, the purity of the prepared hydrofluoric acid is high, and the practical value is high.